Biophysical studies in the 1950ies and 1960ies led to the realization that the water
permeability of certain biological membranes must be due to the presence of water …

A generation of research in multiple laboratories led to the prediction that water selective
channels must exist in the plasma membranes of red cells and a variety of 'leaky'epithelia in …

The aquaporins (AQPs) are a family of intrinsic membrane proteins that function as water-
selective channels in the plasma membranes of the cells of many water-transporting tissues …

A critical analysis of the discovery of the first water channel protein (later called aquaporin 1)
has been performed. In 1986 Benga's group in Cluj-Napoca, Romania, published in …

After a decade of work on the water permeability of red blood cells (RBC) Benga group in
Cluj-Napoca, Romania, discovered in 1985 the first water channel protein in the RBC …

The study of water transport began long before the molecular identification of water
channels with studies of water-permeable tissues. The discovery of the first aquaporin …

Water transport across the plasma membrane is important for fluid absorption and/or
secretion as well as cell volume regulation. Water is transported through biological …

Transport of water and salt across cell membranes is of fundamental importance for all
cellular function, and transport of water across epithelia in, among others, kidney, heart and …

Peter C. Agre, an American Society of Nephrology member, is the recipient of the 2003
Nobel Prize in Chemistry for his discovery of the aquaporin water channels. The function of …

Giuseppe Calamita has kindly asked me to contribute a note for the series of publications
related to aquaporins. This topic has consumed my attention for more than a decade, and I …