Cryptococcus neoformans strains exhibit variability in their capsular polysaccharide, cell
morphology, karyotype, and virulence, but the relationship between these variables is poorly …

Microorganisms that live in fluctuating environments must constantly adapt their behavior to
survive. The host constitutes an important microenvironment in opportunistic and primary …

Cryptococcus neoformans is a major fungal pathogen for patients with debilitated immune
systems. However, no information is available on the stability of virulence or of phenotypes …

Phenotypic switching has been linked to the virulence of many pathogens, including fungi.
However, it has not been conclusively shown to occur in vivo or to influence the outcome of …

Although morphological transitions (such as hyphae and pseudohyphae formation) are a
common feature among fungi, the encapsulated pathogenic yeast Cryptococcus neoformans …

Cryptococcus neoformans strains exhibit considerable phenotype variability with regards to
the capsular polysaccharide, sterol composition of the cell wall, and cell and colony …

We demonstrated the diversity of Cryptococcus neoformans var. gattii strains by a sequence
analysis of multiple genes:(i) the intergenic spacer (IGS) 1 and 2 regions of the rRNA …

The human pathogenic fungus Cryptococcus neoformans exhibits the phenomenon of
phenotypic switching, a process that generates variant colonies that can differ in …

Cryptococcus neoformans is an encapsulated opportunistic organism that can undergo
phenotypic switching. In this process, the parent smooth colony (SM) switches to a more …

This is the first report of a Cryptococcus neoformans var. gattii strain (serotype B) that
switches reversibly between its parent mucoid (NP1-MC) colony morphology and a smooth …