Anticancer agents from diverse natural sources

J Khazir, DL Riley, LA Pilcher… - Natural product …, 2014 - journals.sagepub.com
This review attempts to portray the discovery and development of anticancer agents/drugs
from diverse natural sources. Natural molecules from these natural sources including plants …

Novel anticancer agents from plant sources

U Shah, R Shah, S Acharya, N Acharya - Chinese journal of natural …, 2013 - Elsevier
Plants remain an important source of new drugs, new drug leads and new chemical entities.
Plant based drug discovery resulted mainly in the development of anticancer and anti …

Natural products in cancer chemotherapy: past, present and future

J Mann - Nature Reviews Cancer, 2002 - nature.com
Natural products have been the mainstay of cancer chemotherapy for the past 30 years.
However, the quickening pace of (aberrant) gene identification, and the new technologies of …

Research advances on anti-cancer natural products

M Guo, J Jin, D Zhao, Z Rong, LQ Cao, AH Li… - Frontiers in …, 2022 - frontiersin.org
Malignant tumors seriously threaten people's health and life worldwide. Natural products,
with definite pharmacological effects and known chemical structures, present dual …

Roles of pyridine and pyrimidine derivatives as privileged scaffolds in anticancer agents

S Prachayasittikul, R Pingaew… - Mini Reviews in …, 2017 - ingentaconnect.com
Background: Cancer has been considered to be a global health concern due to the impact of
disease on the quality of life. The continual increase of cancer cases as well as the …

The anticancer effect of natural plant alkaloid isoquinolines

D Yun, SY Yoon, SJ Park, YJ Park - International Journal of Molecular …, 2021 - mdpi.com
Isoquinoline alkaloids-enriched herbal plants have been used as traditional folk medicine
for their anti-inflammatory, antimicrobial, and analgesic effects. They induce cell cycle arrest …

Anticancer natural medicines: An overview of cell signaling and other targets of anticancer phytochemicals

MF Akhtar, A Saleem, A Rasul, MMFA Baig… - European Journal of …, 2020 - Elsevier
Therapies of cancer are as diverse as multifaceted the cancer is. Anticancer drugs include,
but not limited to synthetic, semisynthetic and natural drugs and monoclonal antibodies. A …

Tumor microenvironment: a prospective target of natural alkaloids for cancer treatment

Y Luo, S Yin, J Lu, S Zhou, Y Shao, X Bao… - Cancer Cell …, 2021 - Springer
Malignant tumor has become one of the major diseases that seriously endangers human
health. Numerous studies have demonstrated that tumor microenvironment (TME) is closely …

Modulation of multiple signaling pathways of the plant-derived natural products in cancer

L Sun, W Zhou, H Zhang, Q Guo, W Yang, B Li… - Frontiers in …, 2019 - frontiersin.org
Natural compounds are highly effective anticancer chemotherapeutic agents, and the targets
of plant-derived anticancer agents have been widely reported. In this review, we focus on …

Cancer wars: natural products strike back

C Basmadjian, Q Zhao, E Bentouhami, A Djehal… - Frontiers in …, 2014 - frontiersin.org
Natural products have historically been a mainstay source of anticancer drugs, but in the
90's they fell out of favor in pharmaceutical companies with the emergence of targeted …