Flexible modeling of the effects of continuous prognostic factors in relative survival

A Mahboubi, M Abrahamowicz, R Giorgi… - Statistics in …, 2011 - Wiley Online Library
Relative survival methods permit separating the effects of prognostic factors on disease‐
related 'excess mortality'from their effects on other‐causes 'natural mortality', even when …

Additive and multiplicative covariate regression models for relative survival incorporating fractional polynomials for time‐dependent effects

PC Lambert, LK Smith, DR Jones… - Statistics in …, 2005 - Wiley Online Library
Relative survival is used to estimate patient survival excluding causes of death not related to
the disease of interest. Rather than using cause of death information from death certificates …

Dynamic regression hazards models for relative survival

G Cortese, TH Scheike - Statistics in Medicine, 2008 - Wiley Online Library
A natural way of modelling relative survival through regression analysis is to assume an
additive form between the expected population hazard and the excess hazard due to the …

Joint model for left‐censored longitudinal data, recurrent events and terminal event: Predictive abilities of tumor burden for cancer evolution with application to the …

A Król, L Ferrer, JP Pignon, C Proust‐Lima… - …, 2016 - Wiley Online Library
In oncology, the international WHO and RECIST criteria have allowed the standardization of
tumor response evaluation in order to identify the time of disease progression. These semi …

A joint frailty model to estimate the recurrence process and the disease‐specific mortality process without needing the cause of death

A Belot, V Rondeau, L Remontet, R Giorgi… - Statistics in …, 2014 - Wiley Online Library
In chronic diseases, such as cancer, recurrent events (such as relapses) are commonly
observed; these could be interrupted by death. With such data, a joint analysis of recurrence …

Analysis of time‐dependent covariates in a regressive relative survival model

R Giorgi, J Gouvernet - Statistics in medicine, 2005 - Wiley Online Library
Relative survival is a method for assessing prognostic factors for disease-specific mortality.
However, most relative survival models assume that the effect of covariate on disease …

A statistical model for the dependence between progression‐free survival and overall survival

F Fleischer, B Gaschler‐Markefski… - Statistics in …, 2009 - Wiley Online Library
Among the surrogate endpoints for overall survival (OS) in oncology trials, progression‐free
survival (PFS) is more and more taking the leading role. Although there have been some …

An overall strategy based on regression models to estimate relative survival and model the effects of prognostic factors in cancer survival studies

L Remontet, N Bossard, A Belot, J Esteve… - Statistics in …, 2007 - Wiley Online Library
Relative survival provides a measure of the proportion of patients dying from the disease
under study without requiring the knowledge of the cause of death. We propose an overall …

Hazard regression model and cure rate model in colon cancer relative survival trends: are they telling the same story?

T Bejan-Angoulvant, AM Bouvier, N Bossard… - European journal of …, 2008 - Springer
Hazard regression models and cure rate models can be advantageously used in cancer
relative survival analysis. We explored the advantages and limits of these two models in …

Joint estimation of time‐dependent and non‐linear effects of continuous covariates on survival

M Abrahamowicz, TA MacKenzie - Statistics in medicine, 2007 - Wiley Online Library
In order to yield more flexible models, the Cox regression model, λ (t; x)= λ0 (t) exp (βx), has
been generalized using different non‐parametric model estimation techniques. One …