In the demanding field of proteomics, there is an urgent need for affinity-catcher molecules to
implement effective and high throughput methods for analysing the human proteome or …

Technologies to develop and evolve the function of proteins and, in particular, antibodies
have developed rapidly since the introduction of phage display. Importantly, it has become …

To define the proteome of an organism, there is a need for robust and reproducible methods
for the quantitative detection of all the polypeptides in a cell. High-density arrays of receptors …

We have developed a screening method that has the potential to streamline the high-
throughput analysis of affinity reagents for proteomic projects. By using multiplexed flow …

Engineered affinity proteins have, together with antibodies and antibody derivatives,
become indispensable tools in many areas of life science and with an increasing number of …

The number of orphan receptors and antibodies may diminish in the future thanks to the
emergence of novel experimental strategies which could facilitate the identification and …

Antibody-based proteomics offers distinct advantages in the analysis of complex samples for
discovery and validation of biomarkers associated with disease. However, its large-scale …

Natural molecules such as proteins and carbohydrates, which by their nature bind to target
proteins with high specificity, are plausible candidates to function as affinity “ligands” for …

In recent years, several cell-based screening technologies for the isolation of antibodies with
prescribed properties emerged. They rely on the multi-copy display of antibodies or antibody …

A strategy for high-throughput evaluation of combinatorial compound libraries is reported,
which circumvents the necessity to test complex mixtures. The method is based on a new …