Endobiotic metabolites are associated with biological processes in the body and therefore
may serve as biomarkers for disease states or therapeutic efficacy and toxicity. However …

Understanding how metabolites are longitudinally influenced by age and sex could facilitate
the identification of metabolomic profiles and trajectories that indicate disease risk. We …

Serum and plasma are commonly used in metabolomic-epidemiology studies. Their
metabolome is susceptible to differences in pre-analytical conditions and the impact of this is …

Serum metabolites can reflect the diffusion/export of biochemicals from various organs. They
can serve as biomarkers related to diseases and therapeutic efficacy/toxicity. While studies …

Objective Although metabolic profiles have been associated with chronic disease risk, lack
of temporal stability of metabolite levels could limit their use in epidemiological …

Plasma metabolomics holds potential for precision medicine, but limited information is
available to compare the performance of such methods across multiple cohorts. We …

Objective: It is well established that disease states are associated with biochemical changes
(eg, diabetes/glucose, cardiovascular disease/cholesterol), as are responses to chemical …

Metabolic syndrome (MetS) affects an increasing number of older adults worldwide. Cross-
cultural comparisons can provide insight into how factors, including genetic, environmental …

Understanding the complexity of aging is of utmost importance. This can now be addressed
by the novel and powerful approach of metabolomics. However, to date, only a few …

Metabolomics is a powerful technology with broad applications in life science that, like other-
omics approaches, requires high-quality samples to achieve reliable results and ensure …