Sweet Taste Receptors and Associated Sweet Peptides: Insights into Structure and Function

S Zhao, H Zheng, Y Lu, N Zhang… - Journal of Agricultural …, 2023 - ACS Publications
Long-term consumption of a high-sugar diet may contribute to the pathogenesis of several
chronic diseases, such as obesity and type 2 diabetes. Sweet peptides derived from a wide …

Natural sweet macromolecules: how sweet proteins work

PA Temussi - Cellular and Molecular Life Sciences CMLS, 2006 - Springer
A few proteins, discovered mainly in tropical fruits, have a distinct sweet taste. These
proteins have played an important role towards a molecular understanding of the …

New insight into the structure-activity relationship of sweet-tasting proteins: protein sector and its role for sweet properties

X Zhao, C Wang, Y Zheng, B Liu - Frontiers in nutrition, 2021 - frontiersin.org
Sweet-tasting protein is a kind of biomacromolecule that has remarkable sweetening power
and is regarded as the promising sugar replacer in the future. Some sweet-tasting proteins …

Identifying the interactions between natural, non-caloric sweeteners and the human sweet receptor by molecular docking

W Acevedo, CA Ramírez-Sarmiento, E Agosin - Food chemistry, 2018 - Elsevier
Natural sweeteners, such as stevia and thaumatin, exert their sweet taste by specifically
binding to sweet taste receptors. However, the molecular basis of their sweetening power …

Recent advances in taste transduction mechanism, analysis methods and strategies employed to improve the taste of taste peptides

C Song, Z Wang, H Li, W Cao, Z Chen… - Critical Reviews in …, 2023 - Taylor & Francis
Taste peptides are oligopeptides that enhance both aroma and taste of food, and they are
classified into five categories based on their taste characteristics: salty, sour, umami, sweet …

Human sweet taste receptor: complete structure prediction and evaluation

A Shrivastav, S Srivastava - … Journal of Chemical and Analytical Science, 2013 - Elsevier
Abstract Aims/Background Human sweet taste receptor structure is predicted and was
further evaluate using experimental result. This would enable receptor-based docking and …

Sweet proteins–potential replacement for artificial low calorie sweeteners

R Kant - Nutrition journal, 2005 - Springer
Exponential growth in the number of patients suffering from diseases caused by the
consumption of sugar has become a threat to mankind's health. Artificial low calorie …

Sweetness chemoreception theory and sweetness transduction

SC Eggers, TE Acree, RS Shallenberger - Food Chemistry, 2000 - Elsevier
This review summarizes the outcome of sweet taste chemoreception research over the last
30 years. Since the sweet taste receptor has yet to be isolated and identified, several models …

The history of sweet taste: not exactly a piece of cake

P Temussi - Journal of Molecular Recognition: An …, 2006 - Wiley Online Library
Understanding the molecular bases of sweet taste is of crucial importance not only in
biotechnology but also for its medical implications, since an increasing number of people is …

Structure-dependent activity of plant-derived sweeteners

SS Ҫiçek - Molecules, 2020 - mdpi.com
Human sensation for sweet tastes and the thus resulting over-consumption of sugar in
recent decades has led to an increasing number of people suffering from caries, diabetes …