Manual intervention is usually required in the multiple rounds of refinement of protein crystal
structures, including linking and/or extending the fragments of the initial model and …

A computer program, called OOPS, is described which facilitates and speeds up the process
of rebuilding a protein structure inside its electron density and reduces the chances of local …

Advances in protein model refinement techniques are required as diverse sources of protein
structure information are available from low‐resolution experiments or informatics‐based …

The number of macromolecular structures deposited in the Protein Data Bank now
approaches 100 000, with the vast majority of them determined by crystallographic methods …

Several methods to assess the (dis) similarity of protein structures objectively are described,
some of which, when applied to non-crystallographically related protein models, are able to …

Correctly positioning ideal protein fragments by molecular replacement presents an
attractive method for obtaining preliminary phases when no template structure for molecular …

EDPDB is a Fortran program that simplifies the analysis of protein structure and makes it
easy to extract various types of geometrical and biologically relevant information for the …

The emergence of structure-determination initiatives that employ high-throughput protein
crystallography emphasizes the need to establish quality-control methods for screening the …

The number of macromolecular structures deposited in the Protein Data Bank now exceeds
45 000, with the vast majority determined using crystallographic methods. Thousands of …

This paper describes the design and full implementation of a new concept in data deposition
and validation: AutoDep (copyright Brookhaven Science Associates LLC). AutoDep changes …