Anti-Influenza Virus Activities of 4-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)amino]-N-(4,6-dimethyl-2-pyrimidin-2-yl)benzenesulphonamide and its Derivatives

P Selvam, N Murugesh… - Antiviral Chemistry …, 2006 - journals.sagepub.com
4-[(1, 2-Dihydro-2-oxo-3H-indol-3-ylidene) amino]-N-(4, 6-dimethyl-2-pyrimidinyl)-
benzenesulphonamide (SPIII-5H) and related compounds were tested for antiviral activity …

Design, Synthesis, and Biological Evaluation of New 8‐Trifluoromethylquinoline Containing Pyrazole‐3‐carboxamide Derivatives

N Nayak, J Ramprasad… - Journal of Heterocyclic …, 2017 - Wiley Online Library
The article describes the design, synthesis, and characterization of a new series of 8‐
trifluoromethylquinoline substituted pyrazole‐3‐carboxamides (9a, 9b, 9c, 9d, 9e, 9f, 9g, 9h …

Evaluation of some new heterocycles bearing 2‐oxoquinolyl moiety as immunomodulator against highly pathogenic avian influenza virus (H5N8)

EAE El‐Helw, ARI Morsy… - Journal of Heterocyclic …, 2021 - Wiley Online Library
The hydrazide obtained from furan‐2 (3 H)‐one integrated with a quinolin‐2 (1 H)‐one core
reported previously by our research group was utilized as a building block synthon to obtain …

Furan-carboxamide derivatives as novel inhibitors of lethal H5N1 influenza A viruses

Y Yu, J Zheng, L Cao, S Li, X Li, HB Zhou, X Liu, S Wu… - RSC …, 2017 - pubs.rsc.org
In this study, we reported the synthesis and biological characterization of a novel series of
furan-carboxamide derivatives that were potent inhibitors of the influenza A H5N1 virus. The …

Novel 3-(2-adamantyl) pyrrolidines with potent activity against influenza A virus—identification of aminoadamantane derivatives bearing two pharmacophoric amine …

G Stamatiou, A Kolocouris, N Kolocouris… - Bioorganic & medicinal …, 2001 - Elsevier
The 3-(2-adamantyl) pyrrolidines 8a–g, 14 were synthesized and evaluated for activity
against influenza A virus. The parent N–H compound 14 was several times more active than …

Aliphatic and alicyclic camphor imines as effective inhibitors of influenza virus H1N1

AS Sokolova, ОI Yarovaya, DS Baev… - European journal of …, 2017 - Elsevier
A series of camphor derived imines was synthesised and evaluated in vitro for antiviral
activity. Theoretical evaluations of ADME properties were also carried out. Most of these …

Antiviral properties of 3-quinolinecarboxamides: a series of novel non-nucleoside antiherpetic agents.

MP Wentland, RB Perni, PH Dorff… - Drug design and …, 1997 - europepmc.org
Novel antiherpetic 3-quinolinecarboxamides were discovered as part of a drug discovery
program at Sterling Winthrop Inc. A major goal of this research was to identify novel non …

Synthesis of 3, 6, 7-substituted-quinoxalin-2-ones for evaluation of antimicrobial and anticancer activity. Part 2

P Sanna, A Carta, M Loriga, S Zanetti, L Sechi - Il Farmaco, 1999 - Elsevier
Synthesis of 3,6,7-substituted-quinoxalin-2-ones for evaluation of antimicrobial and
anticancer activity. Part 2 - ScienceDirect Skip to main contentSkip to article Elsevier logo …

Microwave-irradiated synthesis and antimicrobial activity of 2-phenyl-7-substitutedalkyl/arylaminoquinoline-4-carboxylic acid derivatives

HG Bhatt, YK Agrawal - Medicinal chemistry research, 2010 - Springer
This report focuses on the synthesis of 2-phenyl-7-substitutedquinoline-4-carboxylic acid
derivatives through both conventional and microwave-irradiated methods. Intermediate 7 …

Synthesis and in vitro study of novel neuraminidase inhibitors against avian influenza virus

J Kongkamnerd, L Cappelletti, A Prandi… - Bioorganic & medicinal …, 2012 - Elsevier
Evidences of oseltamivir resistant influenza patients raised the need of novel neuraminidase
inhibitors. In this study, five oseltamivir analogs PMC-31–PMC-36, synthesised according to …