(Naphthalen-1-ylmethylene)-5-phenylfuran-2 (3 H)-one 1 was prepared and converted into
a variety of heterocyclic systems of synthetic and biological importance. Benzylamine was …

A new series of fused pyran derivatives 5a–x bearing 2-morpholinoquinoline nucleus has
been synthesized under microwave irradiation by a reaction of 2-morpholinoquinoline-3 …

Reaction of the quinolone carboxylic acids 1 and 2 with (2-acetoxyethoxy) methyl chloride 3
in the presence of n-Bu4NI afforded the N-alkylated products 4 and 6, which could be …

This article describes the synthesis and antiviral activity evaluation of new substituted 1, 2, 4-
oxadiazoles containing a bicyclic substituent at position 5 of the heterocycle and O-acylated …

New routes for the synthesis of aminoquinolizinone derivatives with interesting biological
activities are reported. Reactions enaminones 2 and 9 with malononitrile affords …

A new class of compounds featuring a camphor moiety has been discovered that exhibits
potent inhibitory activity against influenza A (H1N1) pdm09 and A (H5N1) viruses. The …

A series of novel 6-fluoro-7-diazabicycIoalkylquinolonecarboxylic acids substituted with
various C8 (H, F, Cl, N) and Nx (ethyl, cyclopropyl, vinyl, 2-fluoroethyl, 4-fluorophenyl, 2, 4 …

A new series of N-arylamino biquinoline derivatives 5a-x were synthesized by reaction of 2-
chloro-3-formyl quinolines 2a–d with malononitrile and various enhydrazinoketones 4a–f in …

A series of novel 6-fluoro-7-(5-alkyl-1, 3, 4-thiadiazol/oxadiazol-2-ylsulfanyl)-4-quinolone-3-
carboxylic acids were synthesized using microwave irradiation. The compounds were tested …

More effective prophylactic and therapeutic strategies to combat influenza viruses are
urgently required worldwide because the conventional anti-influenza drugs are facing drug …