Capsaicin was postulated to exert its pharmacological actions by interacting at a specific
recognition site (receptor) expressed predominantly by primary afferent neurons. 2. The …

Sensory neurons sensitive to vanilloids (the paradigm of which is capsaicin, the pungent
principle in hot peppers) were visualized by [3H] resiniferatoxin (RTX) autoradiography in …

The theory for the existence of a common pharmacological receptor for capsaicin, piperin
and ethanolamides with a long alkyl chain, designated as the 'capsaicin receptor', was …

Specific binding of [3 H] resiniferatoxin (RTX) is thought to represent the vanilloid (capsaicin)
receptor. In the present study, we have used this binding assay to identify for the first time a …

Capsazepine was reported to block capsaicin-and resiniferatoxin (RTX)-induced responses
both in vivo and in vitro with Schild plots suggesting a competitive mechanism of action. We …

In the present report we compared the properties of [3 H] resiniferatoxin (RTX) binding by the
vanilloid receptors present at different parts of the primary afferent neurons of the rat. We …

In the present study a novel 96‐well plate assay system was used to characterize
pharmacologically the vanilloid receptor in the dorsal spinal cord of the rat. When activated …

Definition of the physiological and pharmacological properties of primary afferent neurons
by the use of capsaicin and its analogues (eg resiniferatoxin) has represented one of the …

Vanilloid (capsaicin) receptors were visualized by [3H] resiniferatoxin (RTX)
autoradiography in the brain of newborn as well as adult (both control and colchicine …

Specific binding of [3 H] resiniferatoxin (RTX) is thought to represent the vanilloid (capsaicin)
receptor. In the present study, we have used this binding assay to elucidate the contribution …