Precisely inhibiting excessive intestinal epithelial cell apoptosis to efficiently treat inflammatory bowel disease with oral pifithrin‐α embedded nanomedicine (OPEN)
M Wang, Q Huang, M Liu, T Zhao, X Song… - Advanced …, 2023 - Wiley Online Library
The increased incidence of inflammatory bowel disease (IBD) has seriously affected the life
quality of patients. IBD develops due to excessive intestinal epithelial cell (IEC) apoptosis …
quality of patients. IBD develops due to excessive intestinal epithelial cell (IEC) apoptosis …
Genistein-derived ROS-responsive nanoparticles relieve colitis by regulating mucosal homeostasis
W Fan, S Zhang, Y Wu, T Lu, J Liu, X Cao… - … Applied Materials & …, 2021 - ACS Publications
Disruption of intestinal homeostasis is an important event in the development of
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …
A proresolving peptide nanotherapy for site‐specific treatment of inflammatory bowel disease by regulating proinflammatory microenvironment and gut microbiota
C Li, Y Zhao, J Cheng, J Guo, Q Zhang… - Advanced …, 2019 - Wiley Online Library
The incidence and prevalence of inflammatory bowel disease (IBD) increases steadily
worldwide. There is an urgent need for effective and safe IBD therapies. Accelerated …
worldwide. There is an urgent need for effective and safe IBD therapies. Accelerated …
The progression of inorganic nanoparticles and natural products for inflammatory bowel disease
There is a growing body of evidence indicating a close association between inflammatory
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …
bowel disease (IBD) and disrupted intestinal homeostasis. Excessive production of reactive …
Ultrathin hafnium disulfide atomic crystals with ROS-scavenging and colon-targeting capabilities for inflammatory bowel disease treatment
The exciting success of NBTXR3 in the clinic has triggered a tumult of activities in the design
and development of hafnium-based nanoparticles. However, due to the concerns of …
and development of hafnium-based nanoparticles. However, due to the concerns of …
Emerging nanomedicine and prodrug delivery strategies for the treatment of inflammatory bowel disease
M Sun, W Ban, H Ling, X Yu, Z He, Q Jiang… - Chinese Chemical …, 2022 - Elsevier
Inflammatory bowel disease (IBD) is a chronic and recurrent disease of the gastrointestinal
tract, mainly including Crohn's disease (CD) and ulcerative colitis (UC). However, current …
tract, mainly including Crohn's disease (CD) and ulcerative colitis (UC). However, current …
Reactive Oxygen Species‐Activated CO Versatile Nanomedicine with Innate Gut Immune and Microbiome Remodeling Effects for Treating Inflammatory Bowel …
Y Zeng, M Fan, Q Zhou, D Chen, T Jin… - Advanced Functional …, 2023 - Wiley Online Library
Abnormal activation of the gut mucosal immune system and a highly dysregulated gut
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …
microbiota play essential roles in the progression of inflammatory bowel disease (IBD). The …
Rational design of orally administered cascade nanozyme for inflammatory bowel disease therapy
Y Yu, X Zhao, X Xu, C Cai, X Tang, Q Zhang… - Advanced …, 2023 - Wiley Online Library
Inflammatory bowel disease (IBD) affects millions of individuals worldwide annually. Enteric
reactive oxygen species (ROS) play critical roles in the physiology and pathology of IBD …
reactive oxygen species (ROS) play critical roles in the physiology and pathology of IBD …
ROS Scavenging and inflammation-directed polydopamine nanoparticles regulate gut immunity and flora therapy in inflammatory bowel disease
M Bao, K Wang, J Li, Y Li, H Zhu, M Lu, Y Zhang… - Acta Biomaterialia, 2023 - Elsevier
Dysfunction of the intestinal mucosal immune system and dysbiosis of the intestinal
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …
Probiotic‐inspired nanomedicine restores intestinal homeostasis in colitis by regulating redox balance, immune responses, and the Gut Microbiome
Microbiota‐based therapeutics offer innovative strategies to treat inflammatory bowel
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …
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