Identification and Characterisation of 5‐Hydroxytryptamine3 Recognition Sites in Human Brain Tissue

JM Barnes, NM Barnes, B Costall… - Journal of …, 1989 - Wiley Online Library
[3H] Zacopride displayed regional saturable specific binding to homogenates of human
brain tissues, as defined by the inclusion of BRL43694 [endo‐N‐(9‐methyl‐9‐azabicyclo …

Serotonin increases ERK1/2 phosphorylation in astrocytes by stimulation of 5-HT2B and 5-HT2C receptors

B Li, S Zhang, M Li, L Hertz, L Peng - Neurochemistry international, 2010 - Elsevier
We have previously shown that fluoxetine causes ERK1/2 phosphorylation in cultured
mouse astrocytes mediated exclusively by stimulation of 5-HT2B receptors (Li et al., 2008b) …

Denervation supersensitivity of 5-HT-1c receptors in rat choroid plexus

PJ Conn, A Janowsky, E Sanders-Bush - Brain research, 1987 - Elsevier
Abstract Serotonin (5-HT)-stimulated phosphoinositide hydrolysis in the choroid plexus is
mediated by the 5-HT-1c receptor. The current study demonstrates that treatment of rats with …

Differentiation of 5-hydroxytryptamine2 receptor subtypes using 125I-R-(-) 2, 5-dimethoxy-4-iodo-phenylisopropylamine and 3H-ketanserin

DJ McKenna, SJ Peroutka - Journal of Neuroscience, 1989 - Soc Neuroscience
The radioligand binding characteristics of 125I-R-(-) 4-iodo-2, 5-
dimethoxyphenylisopropylamine [125I-R-(-) DOI] and 3H-ketanserin were compared in rat …

Serotonin 5‐HT2C receptor protein expression is enriched in synaptosomal and post‐synaptic compartments of rat cortex

NC Anastasio, MF Lanfranco, MJ Bubar… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 113, 1504–1515. Abstract The action of serotonin (5‐HT) at the 5‐
HT2C receptor (5‐HT2CR) in cerebral cortex is emerging as a candidate modulator of …

Effect of 5‐HT on binding of [11C] WAY 100635 to 5‐HT1A receptors in rat brain, assessed using in vivo microdialysis and PET after fenfluramine

S Hume, E Hirani, J Opacka‐Juffry, R Myers… - Synapse, 2001 - Wiley Online Library
By using a combination of positron emission tomography (PET) and postmortem tissue
dissection, the effect of increased endogenous serotonin on specific binding of [11C] WAY …

A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation

M Ruat, E Traiffort, JM Arrang… - Biochemical and …, 1993 - Elsevier
Using a strategy based upon nucleotide sequence homology and starting from the
sequence of the rat histamine H 2 receptor (Ruat et al., Biochem. Biophys. Res. Commun …

Presynaptic serotonin receptors in the central nervous system.

M Göthert - Annals of the New York Academy of Sciences, 1990 - europepmc.org
Presynaptic 5-HT autoreceptors have been identified in any region of the mammalian CNS
containing 5-HT nerve terminals that has been investigated for this purpose. They belong to …

Serotonin 5-HT3 receptors in the central nervous system

P Chameau, JA van Hooft - Cell and tissue research, 2006 - Springer
The 5-HT 3 receptor is a ligand-gated ion channel activated by serotonin (5-HT). Although
originally identified in the peripheral nervous system, the 5-HT 3 receptor is also …

The 5-HT1A serotonin receptor is located on calbindin-and parvalbumin-containing neurons in the rat brain

S Aznar, Z Qian, R Shah, B Rahbek, GM Knudsen - Brain research, 2003 - Elsevier
The 5-HT1A receptor is a well-characterized serotonin receptor playing a role in many
central nervous functions and known to be involved in depression and other mental …