Potential Mechanisms Involved in the Negative Coupling Between Serotonin 5‐HT1A Receptors and Carbachol‐Stimulated Phosphoinositide Turnover in the Rat …

Y Claustre, J Benavides, B Scatton - Journal of neurochemistry, 1991 - Wiley Online Library
Serotonin 5‐HT1A receptors have been reported to be negatively coupled to muscarinic
receptor‐stimulated phosphoinositide turnover in the rat hippocampus. In the present study …

Cellular localization of serotonin2A (5HT2A) receptors in the rat brain

T Xu, SC Pandey - Brain research bulletin, 2000 - Elsevier
The serotonin2A (5HT2A) receptors have been shown to play an important role in several
psychiatric disorders, including depression, schizophrenia, and alcoholism. This …

Multiple serotonin receptors: regional distribution and effect of raphe lesions

MA Blackshear, LR Steranka… - European Journal of …, 1981 - Elsevier
These studies confirm and extend the recent work suggesting that [3 H] lysergic acid
dielhylamide (LSD) labels two distinct binding sites in rat brain resembling serotonin (5HT) …

Regional Distribution and Relative Abundance of Serotonin2c Receptors in Human Brain: Effect of Suicide

GN Pandey, Y Dwivedi, X Ren, HS Rizavi… - Neurochemical …, 2006 - Springer
Abnormalities in serotonin receptor subtypes have been observed in the postmortem brain
of suicide victims. We examined the regional distribution of serotonin (5HT) 2C receptor …

Visualization of a novel serotonin recognition site (5-HT1D) in the human brain by autoradiography

C Waeber, MM Dietl, D Hoyer, A Probst, JM Palacios - Neuroscience letters, 1988 - Elsevier
The localization of a novel serotonin (5-hydroxytryptamine, 5-HT) recognition site named 5-
HT 1D was studied by autoradiography in human postmortem brain material. Serotonin-1 …

The 5-HT₃ receptor in mammalian brain: A new target for the development of psychotropic drugs?

JA Apud - Neuropsychopharmacology, 1993 - psycnet.apa.org
Reviews the literature on the specific serotonin receptor, the 5-hydroxytryptamine₃ (5-HT₃)
receptor, including the development of selective drugs active at the 5-HT₃ receptor, 5-HT₃ …

Peripheral serotonin antagonists: failure to antagonize serotonin in brain areas receiving a prominent serotonergic input

HJ Haigler, GK Aghajanian - Journal of Neural Transmission, 1974 - Springer
It has been suggested that drugs block the effects of serotonin (5-HT) in the brain based on
(1) the ability to block the effects of 5-HT on smooth muscle and on invertebrate neurons (eg …

Autoradiographic quantification of serotonin1A receptors in rat brain following antidepressant drug treatment

SA Welner, C De Montigny, J Desroches… - Synapse, 1989 - Wiley Online Library
There is growing evidence that the serotonergic (5‐HT) system is involved in the
pathogenesis and treatment of major depression. The 5‐HT receptor subtype involved in the …

Release‐Regulating Serotonin 5‐HT1D Autoreceptors in Human Cerebral Cortex

G Maura, S Thellung, GC Andrioli… - Journal of …, 1993 - Wiley Online Library
Release‐regulating 5‐hydroxytryptamine (5‐HT) autoreceptors in the rat brain belong to the
5‐HT1B subtype. On the other hand, the human brain seems to lack 5‐HT1B receptors. In …

Labelling of 5‐Hydroxytryptamine3 Receptors with a Novel 5‐HT3 Receptor Ligand, [3H]RS‐42358–197

EHF Wong, DW Bonhaus, I Wu… - Journal of …, 1993 - Wiley Online Library
RS‐42358–197 {(S)‐N‐(1‐azabicyclo [2.2. 2] oct‐3‐yl)‐2, 4, 5, 6‐tetrahydro‐1H‐benzo [de]
isoquinolin‐1‐one hydrochloride} displaced the prototypic 5‐hydroxytryptamine3 (5‐HT3) …