Interplay between SARS-CoV-2 and the type I interferon response

M Sa Ribero, N Jouvenet, M Dreux, S Nisole - PLoS pathogens, 2020 - journals.plos.org
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current COVID-19 pandemic. An unbalanced immune response, characterized by a weak …

Type I interferons in COVID-19 pathogenesis

E Palermo, D Di Carlo, M Sgarbanti, J Hiscott - Biology, 2021 - mdpi.com
Simple Summary The innate antiviral immune response is essential to limit virus replication
at early stages of infection, thus preventing viral spread and pathogenesis. Nevertheless …

Characterization of SARS-CoV-2 evasion: interferon pathway and therapeutic options

M Znaidia, C Demeret, S van der Werf, AV Komarova - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current COVID-19 pandemic. SARS-CoV-2 is characterized by an important capacity to …

Interferon induction, evasion, and paradoxical roles during SARS‐CoV‐2 infection

C Chiale, TT Greene, EI Zuniga - Immunological Reviews, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the causative agent of
coronavirus disease 2019 (COVID‐19), has caused millions of deaths in the past two years …

Type I interferon susceptibility distinguishes SARS-CoV-2 from SARS-CoV

KG Lokugamage, A Hage, M de Vries… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT SARS-CoV-2, a novel coronavirus (CoV) that causes COVID-19, has recently
emerged causing an ongoing outbreak of viral pneumonia around the world. While distinct …

Type I and III interferon responses in SARS-CoV-2 infection

YM Kim, EC Shin - Experimental & molecular medicine, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), the current pandemic disease, is caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Type I and III …

Antagonism of type I interferon by severe acute respiratory syndrome coronavirus 2

H Xia, PY Shi - Journal of Interferon & Cytokine Research, 2020 - liebertpub.com
The coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), warranting urgent study of the molecular …

[HTML][HTML] Dual nature of type I interferons in SARS-CoV-2-induced inflammation

C King, J Sprent - Trends in immunology, 2021 - cell.com
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The ability of our cells to secrete type I …

Innate immune evasion strategies of SARS-CoV-2

JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …

Interferon antagonists encoded by SARS-CoV-2 at a glance

JH Lee, L Koepke, F Kirchhoff, KMJ Sparrer - Medical microbiology and …, 2023 - Springer
The innate immune system is a powerful barrier against invading pathogens. Interferons
(IFNs) are a major part of the cytokine-mediated anti-viral innate immune response. After …