Predicting drug-drug interactions based on integrated similarity and semi-supervised learning

C Yan, G Duan, Y Zhang, FX Wu… - … /ACM transactions on …, 2020 - ieeexplore.ieee.org
A drug-drug interaction (DDI) is defined as an association between two drugs where the
pharmacological effects of a drug are influenced by another drug. Positive DDIs can usually …

ISCMF: Integrated similarity-constrained matrix factorization for drug–drug interaction prediction

N Rohani, C Eslahchi, A Katanforoush - Network Modeling Analysis in …, 2020 - Springer
Drug–drug interaction (DDI) prediction prepares substantial information for drug discovery.
As the exact prediction of DDIs can reduce human health risk, the development of an …

[HTML][HTML] Computational prediction of drug-drug interactions based on drugs functional similarities

R Ferdousi, R Safdari, Y Omidi - Journal of biomedical informatics, 2017 - Elsevier
Therapeutic activities of drugs are often influenced by co-administration of drugs that may
cause inevitable drug-drug interactions (DDIs) and inadvertent side effects. Prediction and …

SSI–DDI: substructure–substructure interactions for drug–drug interaction prediction

AK Nyamabo, H Yu, JY Shi - Briefings in Bioinformatics, 2021 - academic.oup.com
A major concern with co-administration of different drugs is the high risk of interference
between their mechanisms of action, known as adverse drug–drug interactions (DDIs) …

DSN-DDI: an accurate and generalized framework for drug–drug interaction prediction by dual-view representation learning

Z Li, S Zhu, B Shao, X Zeng, T Wang… - Briefings in …, 2023 - academic.oup.com
Drug–drug interaction (DDI) prediction identifies interactions of drug combinations in which
the adverse side effects caused by the physicochemical incompatibility have attracted much …

[HTML][HTML] DDI-PULearn: a positive-unlabeled learning method for large-scale prediction of drug-drug interactions

Y Zheng, H Peng, X Zhang, Z Zhao, X Gao, J Li - BMC bioinformatics, 2019 - Springer
Abstract Background Drug-drug interactions (DDIs) are a major concern in patients'
medication. It's unfeasible to identify all potential DDIs using experimental methods which …

[HTML][HTML] Drug-drug interaction predicting by neural network using integrated similarity

N Rohani, C Eslahchi - Scientific reports, 2019 - nature.com
Abstract Drug-Drug Interaction (DDI) prediction is one of the most critical issues in drug
development and health. Proposing appropriate computational methods for predicting …

A probabilistic approach for collective similarity-based drug–drug interaction prediction

D Sridhar, S Fakhraei, L Getoor - Bioinformatics, 2016 - academic.oup.com
Motivation: As concurrent use of multiple medications becomes ubiquitous among patients, it
is crucial to characterize both adverse and synergistic interactions between drugs. Statistical …

Predicting drug-drug interactions using meta-path based similarities

F Tanvir, MIK Islam, E Akbas - 2021 IEEE Conference on …, 2021 - ieeexplore.ieee.org
Drug-drug interaction (DDI) indicates the event where a particular drug's desired course of
action is modified when taken together with other drugs (s). DDIs may hamper, enhance, or …

[HTML][HTML] A review of approaches for predicting drug–drug interactions based on machine learning

K Han, P Cao, Y Wang, F Xie, J Ma, M Yu… - Frontiers in …, 2022 - frontiersin.org
Drug–drug interactions play a vital role in drug research. However, they may also cause
adverse reactions in patients, with serious consequences. Manual detection of drug–drug …