Small cell lung cancer tumour cells induce regulatory T lymphocytes, and patient survival correlates negatively with FOXP3+ cells in tumour infiltrate
W Wang, P Hodkinson, F McLaren… - … Journal of Cancer, 2012 - Wiley Online Library
Small cell lung cancer (SCLC) kills at least one person every 2 hr in the United Kingdom.
Some patients do relatively well but most have rapidly progressive disease. There is no …
Some patients do relatively well but most have rapidly progressive disease. There is no …
Elevated Circulating CD4+CD25−Foxp3+ Regulatory T Cells in Patients with Nonsmall Cell Lung Cancer
X Hu, Y Gu, S Zhao, S Hua, Y Jiang - Cancer Biotherapy & …, 2019 - liebertpub.com
Abstract Purpose: CD4+ CD25+ Foxp3+ regulatory T (Treg) cell-mediated
immunosuppression has been implicated as a crucial mechanism of tumor immune cell …
immunosuppression has been implicated as a crucial mechanism of tumor immune cell …
The Prevalence of FOXP3+ Regulatory T-Cells in Peripheral Blood of Patients with NSCLC
L Li, QG Chao, LZ Ping, C Xue, ZY Xia… - Cancer Biotherapy …, 2009 - liebertpub.com
We have studied CD4+ CD25highFOXP3+ regulatory T-cells (Tregs) from 51 patients with
non–small-cell lung cancer (NSCLC) and 33 healthy donors. Regulatory T-cells were …
non–small-cell lung cancer (NSCLC) and 33 healthy donors. Regulatory T-cells were …
[HTML][HTML] The prognostic role of circulating CD8+ T cell proliferation in patients with untreated extensive stage small cell lung cancer
Background Immunosuppression caused by tumorigenesis may promote tumor progress
and invasion. Here, we investigated whether the characteristics of circulating T lymphocyte …
and invasion. Here, we investigated whether the characteristics of circulating T lymphocyte …
[HTML][HTML] Foxp3+ regulatory T cells and natural killer cells distinctly infiltrate primary tumors and draining lymph nodes in pulmonary adenocarcinoma
T Schneider, S Kimpfler, A Warth, PA Schnabel… - Journal of thoracic …, 2011 - Elsevier
Introduction: Regulatory T cells (Tregs) can play a key role in suppressing T-cell-mediated
immunity in patients with cancer. In this study, the immune cell composition of the lung tissue …
immunity in patients with cancer. In this study, the immune cell composition of the lung tissue …
Reciprocal CD4+ T-Cell Balance of Effector CD62Llow CD4+ and CD62LhighCD25+ CD4+ Regulatory T Cells in Small Cell Lung Cancer Reflects Disease …
K Koyama, H Kagamu, S Miura, T Hiura… - Clinical cancer …, 2008 - AACR
Purpose: Small cell lung cancer (SCLC) possesses high tendency to disseminate. However,
SCLC patients with paraneoplastic syndrome mediated by immunity against onconeural …
SCLC patients with paraneoplastic syndrome mediated by immunity against onconeural …
Tumor infiltrating Foxp3+ regulatory T‐cells are associated with recurrence in pathologic stage I NSCLC patients
RP Petersen, MJ Campa, J Sperlazza, D Conlon… - Cancer, 2006 - Wiley Online Library
BACKGROUND. Early stage lung cancer has a variable prognosis, and there are currently
no markers that predict which patients will recur. This study examined the relation between …
no markers that predict which patients will recur. This study examined the relation between …
[HTML][HTML] Increase in activated Treg in TIL in lung cancer and in vitro depletion of Treg by ADCC using an antihuman CCR4 mAb (KM2760)
Introduction Tregs infiltrate tumors and inhibit immune responses against them. Methods We
investigated subpopulations of Foxp3+ CD4 T cells previously defined by Miyara et …
investigated subpopulations of Foxp3+ CD4 T cells previously defined by Miyara et …
Foxp3 expressing CD4+ CD25+ and CD8+ CD28− T regulatory cells in the peripheral blood of patients with lung cancer and pleural mesothelioma
F Meloni, M Morosini, N Solari, I Passadore… - Human immunology, 2006 - Elsevier
The role of T regulatory (Treg) cells in human cancer has not yet been clarified. We
assessed the presence and function of CD4+ and CD8+ Treg cell subsets in the peripheral …
assessed the presence and function of CD4+ and CD8+ Treg cell subsets in the peripheral …
[HTML][HTML] The role of immune microenvironment in small-cell lung cancer: distribution of PD-L1 expression and prognostic role of FOXP3-positive tumour infiltrating …
L Bonanno, A Pavan, MV Dieci, E Di Liso… - European journal of …, 2018 - Elsevier
Introduction The prognosis of small-cell lung cancer (SCLC) is dismal and new effective
therapies are needed. Immunotherapy looks promising, but no molecular predictive markers …
therapies are needed. Immunotherapy looks promising, but no molecular predictive markers …
相关搜索
- patient survival tumour cells
- small cell lung cancer
- nonsmall cell lung cancer
- regulatory t lymphocytes tumour cells
- lung cancer immune microenvironment
- lung cancer peripheral blood
- lung cancer pd l1
- regulatory t cells cancer immunotherapy
- lung cancer pleural mesothelioma
- regulatory t cells primary tumors
- foxp3 regulatory t cells in patients
- regulatory t cells disease stage
- regulatory t cells reciprocal cd4
- regulatory t cells pulmonary adenocarcinoma
- regulatory t cells lymph nodes
- patient survival regulatory t lymphocytes