Functional angiotensin II receptors in cultured vascular smooth muscle cells.

S Gunther, RW Alexander, WJ Atkinson… - The Journal of cell …, 1982 - rupress.org
To study cellular mechanisms influencing vascular reactivity, vascular smooth muscle cells
(VSMC) were obtained by enzymatic dissociation of the rat mesenteric artery, a highly …

Angiotensin II-1 receptors mediate both vasoconstrictor and hypertrophic responses in rat aortic smooth muscle cells.

AT Chiu, WA Roscoe, DE McCall, PB Timmermans - Receptor, 1991 - europepmc.org
The receptor subtypes that mediate the vasoconstrictor and hypertrophic responses of AII
were evaluated in cultured aortic smooth muscle cells from rat. The AII receptors were …

Identification and characterization of the high affinity vascular angiotensin II receptor in rat mesenteric artery.

S Gunther, MA Gimbrone Jr, RW Alexander - Circulation Research, 1980 - Am Heart Assoc
To study the physiology of the high affinity vascular smooth muscle receptor for angiotensin
II, we have characterized 125I-angiotensin II binding sites in a participate fraction prepared …

Angiotensin-receptor signaling in cultured vascular smooth muscle cells

JB Smith - American Journal of Physiology-Renal …, 1986 - journals.physiology.org
Functional receptors for angiotensin II (ANG II) are present in smooth muscle cells cultured
from rat aorta. These cells are especially suitable for investigating transmembrane signaling …

[PDF][PDF] Identification and characterization of functional angiotensin II receptors on cultured heart myocytes.

TB Rogers, ST Gaa, IS Allen - Journal of Pharmacology and Experimental …, 1986 - Citeseer
Cultured neonatal rat myocytes have been investigated as a form without changing K.
Conversely, these nucleotides altered potential system to study the molecular mechanism of …

Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle.

CP Sung, AJ Arleth, BL Storer, EH Ohlstein - Journal of Pharmacology and …, 1994 - ASPET
Angiotensin II (AII) has the potential to promote vascular smooth muscle (VSM) hypertrophy
and hyperplasia; however, the mechanisms involved in AII stimulation of VSM growth are not …

Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells.

AA Geisterfer, MJ Peach, GK Owens - Circulation research, 1988 - Am Heart Assoc
We have explored the hypothesis that contractile agonists are important regulators of
smooth muscle cell growth by examining the effects of one potent contractile agonist …

Role of receptor cycling in the regulation of angiotensin II surface receptor number and angiotensin II uptake in rat vascular smooth muscle cells.

ME Ullian, SL Linas - The Journal of clinical investigation, 1989 - Am Soc Clin Investig
In vivo data on the factors controlling angiotensin II (AII) cell surface binding are conflicting.
We studied the specific effects of AII on AII binding in rat mesenteric artery vascular smooth …

Receptor-mediated effects of angiotensin II on growth of vascular smooth muscle cells from spontaneously hypertensive rats.

B Bunkenburg, T van Amelsvoort, H Rogg… - Hypertension, 1992 - Am Heart Assoc
This study examines the effects of angiotensin II on hypertrophy and proliferation of aortic
smooth muscle cells from spontaneously hypertensive and Wistar-Kyoto rats and the …

Identification and characterization of a new binding site for angiotensin II in mouse neuroblastoma neuro-2A cells

S Chaki, T Inagami - Biochemical and biophysical research …, 1992 - Elsevier
Specific binding site for 125 I-angiotensin II (Ang II), with unique pharmacological properties
uncommon to the hitherto recognized receptor subtypes, was observed in mouse …