Cellular energy sensing and signaling by AMP-activated protein kinase
WW Winder, DM Thomson - Cell biochemistry and biophysics, 2007 - Springer
AMP-activated protein kinase (AMPK) is an energy sensing/signaling protein that, when
activated, increases ATP production by stimulating glucose uptake and fatty acid oxidation …
activated, increases ATP production by stimulating glucose uptake and fatty acid oxidation …
AMP-activated protein kinase in metabolic control and insulin signaling
MC Towler, DG Hardie - Circulation research, 2007 - Am Heart Assoc
The AMP-activated protein kinase (AMPK) system acts as a sensor of cellular energy status
that is conserved in all eukaryotic cells. It is activated by increases in the cellular AMP: ATP …
that is conserved in all eukaryotic cells. It is activated by increases in the cellular AMP: ATP …
AMP‐activated protein kinase–development of the energy sensor concept
The LKB1→ AMPK cascade is switched on by metabolic stresses that either inhibit ATP
production (eg hypoxia, hypoglycaemia) or that accelerate ATP consumption (eg muscle …
production (eg hypoxia, hypoglycaemia) or that accelerate ATP consumption (eg muscle …
Functions of AMP‐activated protein kinase in adipose tissue
M Daval, F Foufelle, P Ferré - The Journal of physiology, 2006 - Wiley Online Library
AMP‐activated protein kinase (AMPK) is involved in cellular energy homeostasis. Its
functions have been extensively studied in muscles and liver. AMPK stimulates pathways …
functions have been extensively studied in muscles and liver. AMPK stimulates pathways …
Exercise-induced AMPK activity in skeletal muscle: role in glucose uptake and insulin sensitivity
M Friedrichsen, B Mortensen, C Pehmøller… - Molecular and cellular …, 2013 - Elsevier
The energy/fuel sensor 5′-AMP-activated protein kinase (AMPK) is viewed as a master
regulator of cellular energy balance due to its many roles in glucose, lipid, and protein …
regulator of cellular energy balance due to its many roles in glucose, lipid, and protein …
Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism
DG Hardie - Proceedings of the Nutrition Society, 2011 - cambridge.org
The AMP-activated protein kinase (AMPK) is a sensor of cellular energy status, and a
regulator of energy balance at both the cellular and whole body levels. Although …
regulator of energy balance at both the cellular and whole body levels. Although …
The role of the AMP‐activated protein kinase in the regulation of energy homeostasis
D Carling - Fatty Acids and Lipotoxicity in Obesity and Diabetes …, 2007 - Wiley Online Library
AMP‐activated protein kinase (AMPK) is the downstream component of a protein kinase
cascade that plays a major role in maintaining energy homeostasis. Within individual cells …
cascade that plays a major role in maintaining energy homeostasis. Within individual cells …
The AMPK β2 subunit is required for energy homeostasis during metabolic stress
B Dasgupta, JS Ju, Y Sasaki, X Liu… - … and cellular biology, 2012 - Taylor & Francis
AMP activated protein kinase (AMPK) plays a key role in the regulatory network responsible
for maintaining systemic energy homeostasis during exercise or nutrient deprivation. To …
for maintaining systemic energy homeostasis during exercise or nutrient deprivation. To …
[HTML][HTML] AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism
The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of cellular
energy status, and recent data demonstrate that it also plays a critical role in systemic …
energy status, and recent data demonstrate that it also plays a critical role in systemic …
AMP-activated protein kinase in skeletal muscle: from structure and localization to its role as a master regulator of cellular metabolism
CA Witczak, CG Sharoff, LJ Goodyear - Cellular and Molecular Life …, 2008 - Springer
The AMP-activated protein kinase (AMPK) is a metabolite sensing serine/threonine kinase
that has been termed the master regulator of cellular energy metabolism due to its numerous …
that has been termed the master regulator of cellular energy metabolism due to its numerous …