Herewith we discuss a network model of the epithelial–mesenchymal transition (EMT) based
on our previous proposed framework. The EMT appears as a “first order” phase transition …

We propose a mechanism for avascular, vascular and metastasis tumor growth based on a
chemical network model. Vascular growth and metastasis, appear as a hard phase transition …

We propose a mechanism for avascular tumor growth based on a simple chemical network.
This model presents a logistic behavior and shows a “second order” phase transition. We …

Abstract Epithelial-mesenchymal transition (EMT), a basic developmental process that might
promote cancer metastasis, has been studied from various perspectives. Recently, the early …

We have previously reported that a universal growth law, as proposed by West and
collaborators for all living organisms, appears to be able to describe also the growth of …

A mechanism to describe the apoptosis process at mesoscopic level through p 53 is
proposed in this paper. A deterministic model given by three differential equations is …

We read with great interest the article published by Brú et al. titled ''The Universal Dynamics
of Tumor Growth''(Biophysical Journal 85: 2948–2961). Therein, a number of in vitro growing …

In this report, we aim at presenting a viable strategy for the study of Epithelial-Mesenchymal
Transition (EMT) and its opposite Mesenchymal-Epithelial Transition (MET) by means of a …

Viewing cancer cell populations as trapped in attractors defined by fractal dimensions raises
an obvious question previously addressed by Huang and Kaufmann: how can one perturb …

Epithelial–mesenchymal transition (EMT), as a crucial process in embryonic development
and cancer metastasis, has been investigated extensively. However, how to quantify the …