Evaluation and treatment strategies in patients with schizophrenia and comorbid depression

D McRenolds, P Mehta, HA Nasrallah - Psychiatric Annals, 2013 - journals.healio.com
CME Educational Objectives 1. Understand depression in relation to negative symptoms in
schizophrenia and be able to understand the risk of suicide in patients with schizophrenia. 2 …

The serotonin paradox: negative symptoms and SSRI augmentation

D Zullino, G Bondolfi, P Baumann - International Journal of …, 1998 - Taylor & Francis
Negative symptoms of schizophrenia are often difficult to treat and may be associated with
poorer long-term outcome. As depressive and negative symptoms show some overlap …

Unraveling the Optimal Treatment Approach for Depression in Schizophrenia Spectrum: A Quest for Clarity

SA de Souza Junior, MEC da Rocha… - Journal of Clinical …, 2024 - journals.lww.com
First, the sample used in the study seems to be highly heterogeneous, encompassing
individuals with diverse diagnoses such as schizophrenia, schizotypal personality …

Meta-analysis of Native Studies as Regards the Effectiveness of Antidepressants on Deficit Syndrome of Schizophrenia: A Systematic Review

SS Shafti - Current Psychopharmacology, 2017 - ingentaconnect.com
Background: While negative symptoms are a significant barrier to successful recovery in
patients with schizophrenia, their pharmacotherapy by adjunctive antidepressants has …

Depression in schizophrenia: recognition and management in the USA

SG Siris, D Addington, JM Azorin, IRH Falloon… - Schizophrenia …, 2001 - Elsevier
The recognition of depression as a distinct syndrome within schizophrenia is a relatively
recent development. The International Survey of Depression in Schizophrenia was designed …

Antidepressants versus clozapine in the treatment of depressive syndrome in schizophrenia

M Jašović-Gašić, C Crnobaric, C Miljevic - European …, 1997 - infona.pl
The prevalence of depression in patients with schizophrenia ranges from approximately
25% to 80%, depending on the stage of illness and mental state of the patient studied. This …

Antidepressants for cognitive impairment in schizophrenia—a systematic review and meta-analysis

JA Vernon, E Grudnikoff, AJ Seidman, TW Frazier… - Schizophrenia …, 2014 - Elsevier
Background Cognitive impairment in schizophrenia is disabling, but current treatment
options remain limited. Objective To meta-analyze the efficacy and safety of adjunctive …

M11. Long-Term Antidepressant Treatment for Negative Symptoms in Schizophrenia: The ACTIONS Study

T Barnes, V Leeson, C Paton, D Osborn… - Schizophrenia …, 2017 - academic.oup.com
Background: The negative symptoms of schizophrenia represent deficiencies in emotional
responsiveness, motivation and socialization that tend to be persistent despite standard …

[HTML][HTML] Forms of antipsychotic therapy: improved individual outcomes under personalised treatment of schizophrenia focused on depression

Z Babinkostova, B Stefanovski - EPMA Journal, 2011 - Springer
Depressive symptoms are common in schizophrenia and they can occur during any phase
of the disorder. Early diagnosis, adequate differential diagnosis and promptly initiated …

Are antipsychotics or antidepressants needed for psychotic depression? A systematic review and meta-analysis of trials comparing antidepressant or antipsychotic …

A Farahani, CU Correll - Journal of Clinical Psychiatry, 2012 - psychiatrist.com
Objective: To perform a meta-analysis of antidepressant-antipsychotic cotreatment versus
antidepressant or antipsychotic monotherapy for psychotic depression. Data Sources: We …