Two isolated-perfused kidney methods were used to study the effects of hypothermic
preservation on renal function in dog kidneys. The isolated-machine-perfused kidney (IMPK) …

The thesis describes the development of a transportable normothermic kidney preservation
device which is able to perfuse discarded human and porcine kidneys for up to 24 hours for …

The role of renal cortical and medullary hypoxia in the development of acute kidney injury is
controversial, partly due to a lack of techniques for the long-term measurement of intrarenal …

Background. Ischaemic kidney injury continues to play a dominant role in the pathogenesis
of acute renal failure (ARF) in many surgical and medical settings. A major event in the …

Dynamic preservation of organ grafts by hypothermic machine perfusion (HMP) has
regained broader interest to provide better outcome after transplantation. One pivotal aspect …

BACKGROUND: Prolonged cold ischemia is frequently associated with a greater risk of
delayed graft function and enhanced graft failure. We hypothesized that media, combining a …

Objective: To evaluate the clinical safety and efficacy of the retrograde perfusion technique
in kidney transplantation. Methods: Between January 2001 and June 2011, 24 cases of …

Background Many kidneys are rejected for transplantation due to inadequate in situ
perfusion during organ retrieval because of the risk of additional ischaemic injury and …

We have evaluated the use of dispersed fluorochemicals in cryoprecipitated plasma as a
perfusage for renal preservation. FC-43 (47) has been shown to be a superior perfusate to …

Objective To investigate the short-and medium-term renal hemodynamic and functional
responses to both short and sustained hypoperfusion. Subjects Eleven Merinos ewes …