Gene–environment interactions in psychiatry: joining forces with neuroscience
A Caspi, TE Moffitt - Nature Reviews Neuroscience, 2006 - nature.com
Gene–environment interaction research in psychiatry is new, and is a natural ally of
neuroscience. Mental disorders have known environmental causes, but there is …
neuroscience. Mental disorders have known environmental causes, but there is …
Measured gene-environment interactions in psychopathology: Concepts, research strategies, and implications for research, intervention, and public understanding of …
TE Moffitt, A Caspi, M Rutter - Perspectives on Psychological …, 2006 - journals.sagepub.com
There is much curiosity about interactions between genes and environmental risk factors for
psychopathology, but this interest is accompanied by uncertainty. This article aims to …
psychopathology, but this interest is accompanied by uncertainty. This article aims to …
Gene–environment interactions in common mental disorders: an update and strategy for a genome-wide search
R Uher - Social psychiatry and psychiatric epidemiology, 2014 - Springer
A decade of research has demonstrated the explanatory potential of interplay between
genetic variants and environmental factors in the development of common mental disorders …
genetic variants and environmental factors in the development of common mental disorders …
Gene-environment interactions in psychiatry: recent evidence and clinical implications
Abstract Purpose of Review We identify the recent evidence for gene-by-environment
interaction studies in relation to psychiatric disorders. We focus on the key genotypic data as …
interaction studies in relation to psychiatric disorders. We focus on the key genotypic data as …
Gene–environment interplay and psychopathology: Multiple varieties but real effects
M Rutter, TE Moffitt, A Caspi - Journal of child Psychology and …, 2006 - Wiley Online Library
Gene–environment interplay is a general term that covers several divergent concepts with
different meanings and different implications. In this review, we evaluate research evidence …
different meanings and different implications. In this review, we evaluate research evidence …
Etiology in psychiatry: embracing the reality of poly‐gene‐environmental causation of mental illness
Intriguing findings on genetic and environmental causation suggest a need to reframe the
etiology of mental disorders. Molecular genetics shows that thousands of common and rare …
etiology of mental disorders. Molecular genetics shows that thousands of common and rare …
Gene-environment interaction and psychiatric disorders: Review and future directions
Empirical studies suggest that psychiatric disorders result from a complex interplay between
genetic and environmental factors. Most evidence for such gene-environment interaction …
genetic and environmental factors. Most evidence for such gene-environment interaction …
Gene–environment correlations: A review of the evidence and implications for prevention of mental illness
Family studies have demonstrated genetic influences on environmental exposure: the
phenomenon of gene–environment correlation (rGE). A few molecular genetic studies have …
phenomenon of gene–environment correlation (rGE). A few molecular genetic studies have …
[HTML][HTML] Gene-environment interaction in evolutionary perspective: differential susceptibility to environmental influences
By tradition, psychiatrists have been concerned with the nature, origins, sequelae and
treatment of mental disorders. When it comes to etiology and the role of genetics, psychiatric …
treatment of mental disorders. When it comes to etiology and the role of genetics, psychiatric …
Strategy for investigating interactions between measured genes and measured environments
TE Moffitt, A Caspi, M Rutter - Archives of general psychiatry, 2005 - jamanetwork.com
The purpose of this article is to promote research that tests hypotheses of measured gene-
environment interaction (GxE). A GxE occurs when the effect of exposure to an …
environment interaction (GxE). A GxE occurs when the effect of exposure to an …