Leukemia inhibitory factor (LIF), a member of the interleukin‐6 cytokine family, plays a
complex role in cancer. LIF inhibits the proliferation and survival of several myeloid leukemia …

Increasing evidence indicates that interferon alpha (IFN-α) therapy is an effective treatment
option for a subgroup of patients with chronic hepatitis B virus (HBV) infection. It has been …

Cholangiocarcinoma, which is the most common invasive malignant tumor of the biliary tract,
has poor prognosis. There is evidence suggesting that hypoxia-inducible factor 1α (HIF1α) …

Hepatocellular carcinoma (HCC) is one of the malignant cancers with high incidence and
mortality rates worldwide. RNA‐binding protein eukaryotic initiation Factor 4A‐III (eIF4AIII) is …

Friend leukemia virus integration 1 (Fli‑1) is a newly identified ETS protein, and has critical
roles in many malignancies. However, the physiological characters and potential …

IRF8 is a transcription factor with a critical role in B lymphocyte development and functions.
Its role in human diffuse large B-cell lymphoma (DLBCL), however, remained elusive. In this …

Background Gene targeted therapy refers to any therapy focused on one of the many
biological features of the tumor. Such features are mediated by specific genes that are …

Abstract Objective Interferon‐inducible 16 (IFI 16) is known to involve in p53‐dependent
tumour suppression and also the formation of inflammasome, which function, however …

Nuclear factor-kappaB (NF-κB) is a transcription factor that is activated in various
neoplasms, including gastric cancer. Insulin-like growth factor binding protein-3 (IGFBP-3) is …

Purpose The interferon regulatory factor 2 (IRF-2) acted as a tumor suppressor. We
inspected IRF-2 as a predictor of prognosis in gastric cancer (GC) patients and tried to find …