Galanin, a 29-amino-acid neuropeptide, is generally viewed as an inhibitory
neuromodulator in a variety of central systems. Galanin expression is upregulated in the …

The neuropeptide galanin is widely expressed by many differing subsets of neurons in the
nervous system. There is a marked upregulation in the levels of the peptide in a variety of …

The neuropeptide galanin is widely, but not ubiquitously, expressed in the adult nervous
system. Its expression is markedly up-regulated in many neuronal tissues after nerve injury …

The inhibitory neuropeptide galanin has widespread distribution throughout the central
nervous system. Studies indicate that galanin modulates cognition by regulating cholinergic …

The neuropeptide galanin is an inhibitory modulator of hippocampal acetylcholine (ACh)
release and cognitive functions. Anatomical evidence demonstrated some differences …

Background Galanin is a neuropeptide with a wide distribution in the central and peripheral
nervous systems and whose physiological effects are mediated through three G protein …

Abstract: Galanin (GAL) innervation is hypertrophied in the basal forebrain and cortex of
patients with Alzheimer's disease (AD). Increased GAL could exacerbate the cognitive and …

Multiple Sclerosis (MS) is a demyelinating autoimmune disease of the central nervous
system (CNS) with a presumed autoimmune etiology. Approved treatments for MS are …

In order to further investigate the molecular mechanisms that regulate oligodendrocyte (OC)
survival, we utilized microarrays to characterize changes in OC gene expression after …

The neuropeptide, galanin, and its receptors are localized in the cholinergic basal forebrain
and its projection areas in mammalian brain. Centrally administered galanin inhibits …