The functional interactions of the neuropeptide galanin (GAL) occur through its binding to
three G protein-coupled receptor subtypes: galanin receptor (GALR) 1, GALR2 and GALR3 …

Galanin, a 29-amino acid neuropeptide, is the only peptide known to coexist with
acetylcholine in the basal forebrain neurons which degenerate early in the progression of …

One of the major pathological characteristics of Alzheimer's disease (AD) is the presence of
enhanced deposits of beta-amyloid peptide (Aβ). The neuropeptide galanin (GAL) and its …

Abstract Galanin (GAL) is a 29-amino acid peptide widely distributed in the mammalian
nervous system. Recently, GAL expression has been shown to increase during periods of …

The galanin (GAL) containing peptide fiber system innervates the basal forebrain and has
been shown to hyperinnervate remaining cholinergic neurons in Alzheimer's disease (AD) …

It has previously been shown that the neuropeptide galanin plays a role in the age-
dependent regulation of hippocampal synaptic plasticity and spatial memory. Here, we …

Galanin receptor binding sites were examined in the inferior temporal and medial occipital
gyri of patients with Alzheimer's disease (AD) and matched control subjects using …

The expression of the neuropeptide galanin is markedly up-regulated in many areas of the
central and peripheral nervous system after injury. We have recently demonstrated that …

Galanin is a 29-amino-acid neuropeptide that is widely distributed in the mammalian central
nervous system. Galanin-immunoreactive cell bodies, fibres and terminals, and galanin …

The neuropeptide galanin has been implicated in inhibiting seizures and protecting
hippocampal neurons from excitotoxic injury. In the hippocampus galanin acts through two …