Galanin inhibits acetylcholine release from rat cerebral cortex via a pertussis toxin-sensitive Giprotein

HY Wang, KD Wild, RP Shank, DHS Lee - Neuropeptides, 1999 - Elsevier
Galanin has been implicated in various physiological functions including memory, feeding
and pain perception. Using rat cerebral cortical slices and synaptosome preparations …

Galanin acts as a trophic factor to the central and peripheral nervous systems

SA Hobson, A Bacon, CR Elliot-Hunt, FE Holmes… - Galanin, 2010 - Springer
The neuropeptide galanin is widely, but not ubiquitously, expressed in the adult nervous
system. Its expression is markedly up-regulated in many neuronal tissues after nerve injury …

Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease

SE Counts, B He, S Che, SD Ginsberg… - Neurodegenerative …, 2008 - karger.com
Background: Fibers containing galanin (GAL) enlarge and hyperinnervate cholinergic basal
forebrain (CBF) nucleus basalis (NB) neurons in late-stage Alzheimer's disease (AD), yet the …

Inducible galanin and GalR2 receptor system in motor neuron injury and regeneration

TCD Burazin, AL Gundlach - Journal of neurochemistry, 1998 - Wiley Online Library
Galanin has been ascribed several physiological roles that are thought to be mediated via
multiple galanin receptors. Recently, two galanin receptors—galanin receptor‐1 (GalR1) …

[HTML][HTML] Galanin protects from caspase-8/12-initiated neuronal apoptosis in the ischemic mouse brain via GalR1

Y Li, Z Mei, S Liu, T Wang, H Li, XX Li, S Han… - Aging and …, 2017 - ncbi.nlm.nih.gov
Galanin (GAL) plays key role in many pathophysiological processes, but its role in ischemic
stroke remains unclear. Here, the models of 1 h middle cerebral artery occlusion (MCAO)/1 …

Is galanin a promising therapeutic resource for neural and nonneural diseases?

CM Oliveira Volpe, T Vaz, F Rocha-Silva… - Current Drug …, 2020 - ingentaconnect.com
Background: Galanin (GAL) constitutes a family of neuropeptides composed of four
peptides:(i) galanin (GAL),(ii) galanin-message associated peptide (GAMP),(iii) galanin-like …

Galanin and its receptors in neurological disorders

L Lundström, A Elmquist, T Bartfai, Ü Langel - Neuromolecular medicine, 2005 - Springer
Galanin is a highly inducible neuropeptide, showing distinct up-regulation after pathological
disturbance within the nervous system. Significant increase in galanin expression is …

Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease

SE Counts, EY Chen, S Che, MD Ikonomovic… - Dementia and geriatric …, 2006 - karger.com
Galanin (GAL)-containing fibers enlarge and hyperinnervate remaining cholinergic basal
forebrain (CBF) neurons within the anterior nucleus basalis (NB) in late-stage Alzheimer's …

Phenotypic analysis of boldit Galr1 knockout mice reveals a role for GALR1 galanin receptor in modulating seizure activity but not nerve regeneration

AS Jacoby, FE Holmes, YJ Hort, J Shine… - Letters in Peptide …, 2001 - Springer
The GALR1 galanin receptor is expressed at high levels withinthe central nervous system
and is hypothesised to play asignificant role in many of the central actions of galanin …

Role of galanin receptor 1 and galanin receptor 2 activation in synaptic plasticity associated with 3′, 5′-cyclic AMP response element-binding protein …

H Badie-Mahdavi, X Lu, MM Behrens, T Bartfai - Neuroscience, 2005 - Elsevier
The neuropeptide galanin was shown to impair cognitive performance and reduce
hippocampal CA1 long-term potentiation (LTP) in rodents. However, the contribution of the …