Galanin‐like immunoreactivity is unchanged in Alzheimer's disease and Parkinson's disease dementia cerebral cortex

MF Beal, RA Clevens, GK Chattha… - Journal of …, 1988 - Wiley Online Library
Galanin is a recently isolated neuropeptide that is of particular interest in dementing
disorders because of its known colocalization with choline acetyltransferase in …

Phenotypic analysis of GalR2 knockout mice in anxiety-and depression-related behavioral tests

X Lu, B Ross, M Sanchez-Alavez, EP Zorrilla, T Bartfai - Neuropeptides, 2008 - Elsevier
Neuropeptide galanin modulates a variety of central nervous system functions by signaling
through three G-protein-coupled receptor subtypes, GalR1 through GalR3. Galanin and its …

GalR3 activation promotes adult neural stem cell survival in response to a diabetic milieu

S Mansouri, S Barde, H Ortsäter… - Journal of …, 2013 - Wiley Online Library
Type 2 diabetes impairs adult neurogenesis which could play a role in the CNS
complications of this serious disease. The goal of this study was to determine the potential …

Distribution and differential regulation of galanin receptor subtypes in rat brain: effects of seizure activity

X Lu, A Mazarati, P Sanna, S Shinmei, T Bartfai - Neuropeptides, 2005 - Elsevier
Galanin, acting at the GalR1-3 subtypes of galanin receptors, is involved in the regulation of
cognition, mood, feeding, seizure activity and pain. The understanding of galanin's effects in …

Galanin contributes to monoaminergic dysfunction and to dependent neurobehavioral comorbidities of epilepsy

JS Medel-Matus, D Shin, R Sankar, A Mazarati - Experimental neurology, 2017 - Elsevier
Status epilepticus (SE) in rats, along with chronic epilepsy, leads to the development of
behavioral impairments resembling depressive disorder and/or attention deficit/hyperactivity …

[125I]-Galanin binding in brain of wildtype, and galanin-and GalR1-knockout mice: strain and species differences in GalR1 density and distribution

SRF Jungnickel, AL Gundlach - Neuroscience, 2005 - Elsevier
Widespread production of knockout and transgenic mice has led to an increased use of mice
as animal models for studies of normal-and patho-physiology. Hence, the precise mapping …

[HTML][HTML] The generation of knock-in mice expressing fluorescently tagged galanin receptors 1 and 2

N Kerr, FE Holmes, SA Hobson, P Vanderplank… - Molecular and Cellular …, 2015 - Elsevier
The neuropeptide galanin has diverse roles in the central and peripheral nervous systems,
by activating the G protein-coupled receptors Gal 1, Gal 2 and the less studied Gal 3 (GalR1 …

Galanin down-regulates microglial tumor necrosis factor-α production by a post-transcriptional mechanism

Y Su, D Ganea, X Peng, GM Jonakait - Journal of neuroimmunology, 2003 - Elsevier
The neuropeptide galanin (GAL) is up-regulated following neuronal axotomy or
inflammation. Since other neuropeptides act as immunomodulatory agents, we sought to …

Galanin expressed in the excitatory fibers attenuates synaptic strength and generalized seizures in the piriform cortex of mice

I Schlifke, E Kuteeva, T Hokfelt, M Kokaia - Experimental neurology, 2006 - Elsevier
The neuropeptide galanin is considered to be an endogenous antiepileptic agent,
presumably acting via inhibition of glutamate release. Previously, we have demonstrated …

Galanin antagonizes acetylcholine on a memory task in basal forebrain-lesioned rats.

J Mastropaolo, NS Nadi… - Proceedings of the …, 1988 - National Acad Sciences
Galanin coexists with acetylcholine in medial septal neurons projecting to the ventral
hippocampus, a projection thought to modulate memory functions. Neurochemical lesions of …