In this issue of JAMA, Zhang and colleagues1 report the emergence of a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) variant in Southern California that …

On January 10, 2020, the first genomic sequence of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) isolated from a patient in Wuhan, China, was posted online. As …

The devastating impact of the ongoing COVID-19 pandemic on public health, the economy,
and society has made vaccine development a top priority for global health. Thus, vaccine …

Over the course of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic, the clinical, scientific, and public health communities have had to respond to new …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative virus of the
coronavirus disease 2019 (COVID-19), has been identified in China in late December 2019 …

Methods| Regulatory review with waiver of consent was completed by Cedars-Sinai Medical
Center (CSMC). From all samples from symptomatic inpatients and ambulatory care (urgent …

Background SARS-CoV-2 is an enveloped, positive-sense single-stranded RNA virus with a
30-kilobase genome, which, like all viruses, accumulates nucleotide mutations over time …

Recently emerged variants of SARS-CoV-2 contain in their surface spike glycoproteins
multiple substitutions associated with increased transmission and resistance to neutralising …

The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Recent months have seen surges of SARS-CoV-2 infection across the globe along with
considerable viral evolution. Extensive mutations in the spike protein of variants B. 1.1. 7 …