Asthma is a respiratory disease caused by the interaction of genetic and environmental
factors. The adenylyl cyclase type 9 (ADCY9) enzyme produces the cyclic …

Asthma is a chronic inflammatory disease of the respiratory tract. This heterogeneous
disease is caused by the interaction of interindividual genetic variability and environmental …

What is known and objective: Inhaled combination therapy composing of long‐acting β2‐
agonist and corticosteroid has been widely applied in the management of asthma, but …

Background Asthma is a complex disease characterized by hyperresponsiveness,
obstruction and inflammation of the airways. To date, several studies using different …

Background: Asthma is complex disease which pathogenesis is a mix of environmental and
genetic factors. A predisposition of airways to bronchoconstriction is one of main risk factors …

Background: The β2-adrenergic receptor (ADRB2) is the most common adrenergic receptor
in the lung, and associations between ADRB2 polymorphisms and intermediate phenotypes …

Abstract Background The polymorphism Arg16 in β2‐adrenergic receptor (ADRB2) gene
has been associated with an increased risk of exacerbations in asthmatic children treated …

Background Personalized asthma medicine research identifies critical genes like ADRB2
and ADH5 that affect disease and treatment outcomes, necessitating a deeper exploration of …

Objective: To investigate the association between rs1042713 polymorphisms of ADRB2
gene and the susceptibility of asthma in Chinese Population by meta-analysis. Methods: The …

Background Atopy, an endotype underlying allergic diseases, has a substantial genetic
component. Objective Our goal was to identify novel genes associated with atopy in asthma …