Angiotensin II receptor antagonists in chronic heart failure: where do they fit?

AR Houghton - Drugs, 2002 - Springer
Heart failure is a common and disabling condition with a dismal prognosis. Inhibition of the
renin-angiotensin-aldosterone system (RAAS) with angiotensin converting enzyme (ACE) …

Are angiotensin II receptor blockers indicated in chronic heart failure?

M Komajda - Heart, 2002 - heart.bmj.com
Chronic heart failure is one of the most seri-ous cardiac problems encountered in clinical
practice. Modulation of the renin angiotensin system is a key element in the treatment of this …

Angiotensin antagonism in patients with heart failure: ACE inhibitors, angiotensin receptor antagonists or both?

NLM Cruden, DE Newby - American Journal of Cardiovascular Drugs, 2004 - Springer
Chronic heart failure (CHF) is a major cause of morbidity and mortality in western society. It
is now widely accepted that the renin-angiotensin-aldosterone system (RAAS) and, in …

Angiotensin II receptor blockers for patients with chronic heart failure: The next step forward

Y Sato - Journal of cardiology, 2013 - journal-of-cardiology.com
The renin–angiotensin–aldosterone system (RAAS) is central to the pathogenesis of heart
failure (HF) and medications inhibiting RAAS are critical. Angiotensin-converting enzyme …

The role of angiotensin II receptor blockers in the management of heart failure

JJV McMurray - European heart journal supplements, 2005 - academic.oup.com
Angiotensin-converting enzyme inhibitors (ACE-inhibitors) are first-line treatment for chronic
heart failure (CHF) with a low left ventricular ejection fraction because they improve …

Clinical trials of angiotensin receptor blockers in heart failure: what do we know and what will we learn?

B Pitt - American journal of hypertension, 2002 - academic.oup.com
Although interruption of the renin-angiotensin system with angiotensin converting enzyme
(ACE) inhibitors has evolved as the therapy of choice in heart failure based on large-scale …

Angiotensin II receptor blockers in the treatment of heart failure

RC Peterson, ME Dunlap - Congestive Heart Failure, 2002 - Wiley Online Library
Heart failure treatment centers on antagonism of the renin‐angiotensin‐aldosterone system
and adrenergic nervous system. Angiotensin‐converting enzyme (ACE) inhibitors have …

Angiotensin II receptor blockers in chronic heart failure-Not as ELITE as expected!

CAJ Farquharson, AD Struthers - Journal of the Renin …, 2000 - journals.sagepub.com
For over a decade angiotensin converting enzyme (ACE) inhibitors have revolutionised the
treatment of chronic heart failure, becoming a frontline therapy on the basis of several key …

Angiotensin II receptor blockers in heart failure

JH Patterson - … : The Journal of Human Pharmacology and Drug …, 2003 - Wiley Online Library
Heart failure remains a significant cause of morbidity and mortality, despite major advances
in therapy. Angiotensin II, the principal mediator of the renin‐angiotensin system, exerts both …

[引用][C] The pharmacological management of heart failure: too many treatments?

DJ van Veldhuisen, WH van Gilst - European Journal of Heart …, 2003 - Wiley Online Library
Chronic heart failure (CHF) has become one of the largest medical and epidemiological
problems of the Western world, carrying a high morbidity and mortality. Traditional treatment …