Lessons learned from the valsartan-heart failure trial (Val-HeFT): angiotensin receptor blockers in heart failure

JN Cohn - American Journal of Cardiology, 2002 - ajconline.org
Growing evidence points to a critical pathophysiologic role for angiotensin in the
progression of heart failure and other cardiovascular diseases. This role is probably …

Angiotensin II receptor blockers for the treatment of heart failure: a class effect?

M Hudson, K Humphries, JV Tu… - … : The Journal of …, 2007 - Wiley Online Library
Study Objective. To examine the class effect of angiotensin II receptor blockers (ARBs) on
mortality in patients with heart failure who were aged 65 years or older. Design …

Novel blockers of the renin-angiotensin-aldosterone system in chronic heart failure

A Valluri, AD Struthers, CC Lang - Current heart failure reports, 2014 - Springer
Because of the impressive record of ACE inhibitors in patients with heart failure with reduced
ejection fraction, the renin-angiotensin-aldosterone system continues to be pursued as a …

[引用][C] ACE inhibitor use in heart failure: would that it were so

K Dickstein - European heart journal, 1999 - academic.oup.com
The paper by Bart et al.[1] published in this issue addresses a clinically important issue. It is
well recognised that despite overwhelming evidence confirming the efficacy of ACE …

Maximally recommended doses of angiotensin-converting enzyme (ACE) inhibitors do not completely prevent ACE-mediated formation of angiotensin II in chronic …

UP Jorde, PV Ennezat, J Lisker, V Suryadevara… - Circulation, 2000 - Am Heart Assoc
Background—The added benefits of angiotensin II type I receptor (AT1) blockers (ARBs) to
ACE inhibition suggests that recommended doses of ACE inhibitors provide only partial …

Pharmacotherapy in congestive heart failure: Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in congestive heart failure: do they differ in …

DA Sica - Congestive Heart Failure (Greenwich, Conn.), 2001 - europepmc.org
Angiotensin-converting enzyme (ACE) inhibitors are used in the management of a wide
range of cardiovascular conditions, including congestive heart failure (CHF). Although the …

Angiotensin converting enzyme inhibition in heart failure: clinical trials and clinical practice

IB Squire - Cardiovascular drugs and therapy, 2002 - Springer
Heart failure is a common and often debilitating condition, but one for which there exists a
variety of effective pharmacological therapies. The angiotensin converting enzyme (ACE) …

Exploring new treatment strategies in heart failure

K Swedberg - Blood Pressure, 2000 - Taylor & Francis
Heart failure remains a major and increasing cause of mortality and morbidity, even when
the best available treatments are used. One of its key causes is neuroendocrine activation …

Do angiotensin-converting enzyme inhibitors prolong life in patients with heart failure treated in clinical practice?

M Packer - Journal of the American College of Cardiology, 1996 - Elsevier
Angiotensin converting enzyme (ACE) inhibitors have emerged as a significant advance in
the treatment of heart failure; yet only a minority (ie, 30% to 40%) of eligible patients are …

Angiotensin receptor blockers and clinical trials in heart failure

JN Cohn - European heart journal, 2003 - academic.oup.com
Growing evidence that angiotensin II contributes to the structural abnormalities of the left
ventricle and vasculature that characterize chronic heart failure has made it attractive to …