Glucocorticoid-induced TNF receptor, a costimulatory receptor on naive and activated T cells, uses TNF receptor-associated factor 2 in a novel fashion as an inhibitor …
EM Esparza, RH Arch - The Journal of Immunology, 2005 - journals.aai.org
Glucocorticoid-induced TNFR (GITR) has been implicated as an essential regulator of
immune responses to self tissues and pathogens. We have recently shown that GITR …
immune responses to self tissues and pathogens. We have recently shown that GITR …
[HTML][HTML] Tumor necrosis factor receptor (TNFR)-associated factor 5 is a critical intermediate of costimulatory signaling pathways triggered by glucocorticoid-induced …
EM Esparza, T Lindsten, JM Stockhausen… - Journal of Biological …, 2006 - ASBMB
Tumor necrosis factor receptor (TNFR) family members such as glucocorticoid-induced
TNFR (GITR) control T cell activation, differentiation, and effector functions. Importantly, GITR …
TNFR (GITR) control T cell activation, differentiation, and effector functions. Importantly, GITR …
Glucocorticoid-induced TNF receptor functions as a costimulatory receptor that promotes survival in early phases of T cell activation
EM Esparza, RH Arch - The Journal of Immunology, 2005 - journals.aai.org
Glucocorticoid-induced TNFR (GITR) is a member of the TNFR family that can inhibit the
suppressive function of regulatory T cells and promote the survival and activation of T cells …
suppressive function of regulatory T cells and promote the survival and activation of T cells …
TRAF4 functions as an intermediate of GITR-induced NF-κB activation
EM Esparza, RH Arch - Cellular and Molecular Life Sciences CMLS, 2004 - Springer
Members of the tumor necrosis factor receptor (TNFR) family regulate the activation,
differentiation, and function of many cell types, including cells of the immune system. TNFR …
differentiation, and function of many cell types, including cells of the immune system. TNFR …
[HTML][HTML] Multiple mechanisms for TRAF3-mediated regulation of the T cell costimulatory receptor GITR
Tumor necrosis factor receptor (TNFR)-associated factor 3 (TRAF3) plays context-specific
roles in multiple receptor-mediated signaling pathways in different cell types. Mice lacking …
roles in multiple receptor-mediated signaling pathways in different cell types. Mice lacking …
TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-κB pathway by TRAF-binding TNFRs
J Hauer, S Püschner… - Proceedings of the …, 2005 - National Acad Sciences
TNF family members and their receptors contribute to increased gene expression for
inflammatory processes and intracellular cascades leading to programmed cell death, both …
inflammatory processes and intracellular cascades leading to programmed cell death, both …
Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression
Abstract CD4+ 25+ regulatory T (Treg) cells maintain immunological self-tolerance through
mechanisms that are only in part understood. Previous studies suggest that the …
mechanisms that are only in part understood. Previous studies suggest that the …
GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily
G Nocentini, C Riccardi - European journal of immunology, 2005 - Wiley Online Library
Glucocorticoid‐induced TNFR‐related gene (GITR; TNFRSF18), a receptor belonging to the
TNFR superfamily (TNFRSF), is activated by GITRL. GITR is expressed at low levels on …
TNFR superfamily (TNFRSF), is activated by GITRL. GITR is expressed at low levels on …
Role of the glucocorticoid-induced TNFR-related protein (GITR)-GITR ligand pathway in innate and adaptive immunity
M Azuma - Critical Reviews™ in Immunology, 2010 - dl.begellhouse.com
Glucocorticoid-induced TNF receptor-related protein (GITR) is expressed in regulatory T
cells at high levels, but is also inducible in conventional effector T cells after activation. Initial …
cells at high levels, but is also inducible in conventional effector T cells after activation. Initial …
[PDF][PDF] Signaling triggered by glucocorticoid-induced tumor necrosis factor receptor family-related gene: regulation at the interface between regulatory T cells and …
EM Esparza, RH Arch - Front Biosci, 2006 - Citeseer
Brief history of natural Treg cells 3. Molecular definition of Treg cell function 3.1. FoxP3 is an
essential marker of Treg cells 3.2. IL-2 is a critical regulatory cytokine for Treg cells 3.3 …
essential marker of Treg cells 3.2. IL-2 is a critical regulatory cytokine for Treg cells 3.3 …