Oxidative stress-induced telomeric erosion as a mechanism underlying airborne particulate matter-related cardiovascular disease

TJ Grahame, RB Schlesinger - Particle and fibre toxicology, 2012 - Springer
Particulate matter (PM) pollution is responsible for hundreds of thousands of deaths
worldwide, the majority due to cardiovascular disease (CVD). While many potential …

Environmental pollutants exposure: A potential contributor for aging and age-related diseases

Y Liu, J Wang, Z Huang, J Liang, Q Xia, Q Xia… - Environmental …, 2021 - Elsevier
Telomeres are “protective messengers” at the ends of eukaryotic chromosomes that protect
them from degradation, end to end fusion and recombination. Admittedly, telomeres …

Ageing at the level of telomeres in association to residential landscape and air pollution at home and work: a review of the current evidence

DS Martens, TS Nawrot - Toxicology letters, 2018 - Elsevier
Studies suggest that leukocyte telomere length is an index of systemic ageing. Here, we
discuss telomere length as a marker of biological ageing in relation to residential landscape …

Air pollution stress and the aging phenotype: the telomere connection

DS Martens, TS Nawrot - Current environmental health reports, 2016 - Springer
Aging is a complex physiological phenomenon. The question why some subjects grow old
while remaining free from disease whereas others prematurely die remains largely …

[HTML][HTML] Particulate matter causes telomere shortening and increase in cellular senescence markers in human lung epithelial cells

J Chang-Chien, JL Huang, HJ Tsai, SL Wang… - Ecotoxicology and …, 2021 - Elsevier
Exposure to particulate matter (PM) has been associated with DNA damage, but the
relationships between PM, telomere length and cellular senescence remain unclear. This …

Air pollution exposure and telomere length in highly exposed subjects in Beijing, China: a repeated-measure study

L Hou, S Wang, C Dou, X Zhang, Y Yu, Y Zheng… - Environment …, 2012 - Elsevier
BACKGROUND: Ambient particulate matter (PM) exposure has been associated with short-
and long-term effects on cardiovascular disease (CVD). Telomere length (TL) is a biomarker …

Effects of short-term exposure to inhalable particulate matter on telomere length, telomerase expression, and telomerase methylation in steel workers

L Dioni, M Hoxha, F Nordio, M Bonzini… - Environmental …, 2011 - ehp.niehs.nih.gov
Background Shortened leukocyte telomere length (LTL) is a marker of cardiovascular risk
that has been recently associated with long-term exposure to ambient particulate matter …

Association between leukocyte telomere shortening and exposure to traffic pollution: a cross-sectional study on traffic officers and indoor office workers

M Hoxha, L Dioni, M Bonzini, AC Pesatori… - Environmental …, 2009 - Springer
Background Telomere shortening in blood leukocytes has been associated with increased
morbidity and death from cardiovascular disease and cancer, but determinants of shortened …

[HTML][HTML] Air pollution and telomere length: a systematic review of 12,058 subjects

B Zhao, HQ Vo, FH Johnston… - … diagnosis and therapy, 2018 - ncbi.nlm.nih.gov
Background Over recent decades, adverse effects of ambient air pollution on the
cardiovascular system have been clearly demonstrated. However, the underlying …

Effects of air pollution on telomere length: Evidence from in vitro to clinical studies

P Assavanopakun, R Sapbamrer, S Kumfu… - Environmental …, 2022 - Elsevier
Air pollution remains the major environmental problem globally. There is extensive evidence
showing that the variety of air pollutants from environmental and occupational exposures …