Expression of the SmN splicing protein is developmentally regulated in the rodent brain but not in the rodent heart

K Grimaldi, DA Horn, LD Hudson, G Terenghi… - Developmental …, 1993 - Elsevier
The SmN protein is a tissue-specific splicing factor which is closely related to the ubiquitous
SmB splicing protein but which is expressed only in the adult brain and heart. SmN is also …

Mice lackingSnrpn expression show normal regulation of neuronal alternative splicing events

JD Huntriss, JA Barr, DA Horn, DG Williams… - Molecular Biology …, 1994 - Springer
The SmN protein is closely related to the constitutively expressed RNA splicing protein SmB
but is expressed only in brain and heart tissue. Mice which lack expression of SmN die …

The intronless mouse gene for the tissue specific splicing protein SmN is a processed pseudogene containing a stop codon after thirty-one amino acids

K Grimaldi, D Gerrelli, NG Sharpe, T Lund… - DNA …, 1992 - Taylor & Francis
The SmN protein is a component of small ribonucleoprotein particles which is closely related
to the ubiquitously expressed splicing proteins SmB and B'but is expressed in only a small …

Antagonistic effects of retinoic acid and thyroid hormone on the expression of the tissue-specific splicing protein SmN in a clonal cell line derived from rat heart

D Gerrelli, JD Huntriss, DS Latchman - Journal of molecular and cellular …, 1994 - Elsevier
The SmN protein is a tissue-specific splicing factor which is expressed only in adult heart
brain but not in other tissues. Although a role for SmN in modulating tissue specific …

Expression of the tissue specific splicing protein SmN in neuronal cell lines and in regions of the brain with different splicing capacities

DA Horn, A Suburo, G Terenghi, LD Hudson… - Molecular brain …, 1992 - Elsevier
The SmN protein is closely related to the ubiquitously expressed SmB and B′ RNA splicing
proteins but is expressed in only a limited range of tissues and cell types. The expression of …

The snRNP core protein SmB and tissue-specific SmN protein are differentially distributed between snRNP particles

JD Huntriss, DS Latchman… - Nucleic acids research, 1993 - academic.oup.com
The SmN protein is a tissue specific component of the small nuclear ribonucleoprotein
particle which is closely related to the ubiquitously expressed SmB protein but is expressed …

Cloning and sequencing of a mouse embryonal carcinoma cell mRNA encoding the tissue specific RNA splicing protein SmN.

D Gerrelli, NG Sharpe, DS Latchman - Nucleic acids research, 1991 - ncbi.nlm.nih.gov
Both we (1) and others (2) have reported the detection of a tissue specific protein SmN
which is a component of the spliceosome that mediates the splicing of mRNA precursors …

The cardiac form of the tissue-specific SmN protein is identical to the brain and embryonic forms of the protein

D Gerrelli, K Grimaldi, D Horn, U Mahadeva… - Journal of molecular and …, 1993 - Elsevier
The SmN protein is a component of small nuclear ribonucleoprotein particles and closely
related to the ubiquitously expressed SmB and B'splicing proteins. However, SmN is only …

Expression of the SmB′ splicing protein in rodent cells capable of following an alternative RNA splicing pathway

NG Sharpe, DG Williams, P Norton… - FEBS letters, 1989 - Wiley Online Library
The expression of the SmB and SmB′ spliceosome proteins in a variety of cell types and
tissues has been investigated. Although SmB is found in all cells studied, the SmB′ protein …

Intron 7 conserved sequence elements regulate the splicing of the SMN genes

JT Gladman, DS Chandler - Human genetics, 2009 - Springer
Proximal spinal muscular atrophy (SMA) is a neuromuscular disease caused by low levels of
the survival motor neuron (SMN) protein. In humans there are two nearly identical SMN …