Tinnitus is a maladaptive neuropathic condition that develops in humans and laboratory
animals following auditory insult. In our previous study we demonstrated that sound …

Tinnitus often develops following inner ear pathologies, like acoustic trauma. Therefore, an
acoustic trauma model of tinnitus in gerbils was established using a modulated acoustic …

Gap‐induced prepulse inhibition of acoustic startle (GPIAS) has been used in rats and mice
to study the problem of tinnitus. The current study demonstrates that similar methods can be …

Flavoprotein autofluorescence imaging was used to examine auditory cortical synaptic
responses in aged animals with behavioral evidence of tinnitus and hearing loss. Mice were …

Tinnitus is proposed to be caused by decreased central input from the cochlea, followed by
increased spontaneous and evoked subcortical activity that is interpreted as compensation …

Hyperacusis, a marked intolerance to normal environmental sound, is a common symptom
in patients with tinnitus, Williams syndrome, autism, and other neurologic diseases. It has …

Tinnitus is an auditory phantom percept without external sound sources. Despite the high
prevalence and tinnitus-associated distress of affected patients, the pathophysiology of …

Perceptual abnormalities such as hyperacusis and tinnitus often occur after acoustic
overexposure. Although such exposure can also result in permanent threshold elevation …

Animal models of tinnitus rely on interpretation of behavioural or reflexive tests to determine
the presence of this phantom perception. A commonly used test is the gap prepulse …

Various theories and their associated mechanisms have been proposed as the neural basis
of phantom sound perception (tinnitus), including central gain enhancement and altered …