[HTML][HTML] Clinical significance of microRNAs in chronic and acute human leukemia

CH Yeh, R Moles, C Nicot - Molecular cancer, 2016 - Springer
Small non-coding microRNAs (miRNAs) are epigenetic regulators that target specific cellular
mRNA to modulate gene expression patterns and cellular signaling pathways. miRNAs are …

[HTML][HTML] Dysregulation of miRNA in leukemia: exploiting miRNA expression profiles as biomarkers

L Anelli, A Zagaria, G Specchia, P Musto… - International Journal of …, 2021 - mdpi.com
Micro RNAs (miRNAs) are a class of small non-coding RNAs that have a crucial role in
cellular processes such as differentiation, proliferation, migration, and apoptosis. miRNAs …

Aberrant microRNA expression and its implications in the pathogenesis of leukemias

S Babashah, M Sadeghizadeh, MR Tavirani, S Farivar… - Cellular oncology, 2012 - Springer
Background MicroRNAs (miRNAs) are a class of non-coding, endogenous, small RNAs that
negatively regulate gene expression by inducing degradation or translational inhibition of …

MicroRNAs: a puzzling tool in cancer diagnostics and therapy

B D'ANGELO, E Benedetti, A Cimini… - Anticancer …, 2016 - ar.iiarjournals.org
MicroRNAs (miRNAs) constitute a dominating class of small RNAs that regulate diverse
cellular functions. Due the pivotal role of miRNAs in biological processes, a deregulated …

[HTML][HTML] MicroRNA: A signature for cancer progression

BM Hussen, HJ Hidayat, A Salihi, DK Sabir… - Biomedicine & …, 2021 - Elsevier
MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

MicroRNAs expression signatures are associated with lineage and survival in acute leukemias

Y Wang, Z Li, C He, D Wang, X Yuan, J Chen… - Blood Cells, Molecules …, 2010 - Elsevier
MicroRNAs (miRNAs) are small (∼ 22 nucleotide) non-coding RNAs whose altered
expression has been associated with various types of cancers, including leukemia. In the …

[HTML][HTML] Circulating microRNAs: potential biomarkers for cancer

DC Yu, QG Li, XW Ding, YT Ding - International journal of molecular …, 2011 - mdpi.com
Cancer is the leading cause of death in the world. Development of minimally invasive
biomarkers for early detection of cancer is urgently needed to reduce high morbidity and …

MicroRNA expression and function in cancer

R Garzon, M Fabbri, A Cimmino, GA Calin… - Trends in molecular …, 2006 - cell.com
MicroRNAs are small non-coding RNAs of 19–24 nucleotides in length that downregulate
gene expression during various crucial cell processes such as apoptosis, differentiation and …

MicroRNAs as therapeutic targets in cancer

SP Nana-Sinkam, CM Croce - Translational Research, 2011 - Elsevier
Cancer remains a worldwide epidemic. An improved understanding of the underlying
molecular mechanisms and development of effective targeted therapies are still required for …

MicroRNAs as potential biomarkers in human solid tumors

J Shen, SA Stass, F Jiang - Cancer letters, 2013 - Elsevier
MicroRNAs (miRNAs) regulate the expression of approximately 30% of protein-coding
genes. Functions of miRNAs are essential to maintain a steady state of cellular machinery …