Phagocytosis of invading microorganisms by specialized cells such as macrophages and
neutrophils is a key component of the innate immune response. These cells capture and …

Engagement of immune receptors by antigen may lead to activation, cell proliferation,
differentiation and effector functions. It has recently been proposed that the initiation and …

Several traditionally extracellular pathogens not known to possess invasive capacity have
been shown to invade various mucosal epithelial cells. The mucosal epithelium performs an …

Lipid rafts, also known as microdomains, are important components of cell membranes and
are enriched in cholesterol, glycophospholipids and receptors. They are involved in various …

To effectively combat invading patho-gens, immune cells must rapidly switch from roughly
spherical resting cells to polarized migratory ones, which then move in a directed fashion to …

Lipid rafts, sterol-and sphingolipid-rich membrane microdomains, have been extensively
studied in mammalian cells. Recently, lipid rafts have been shown to control virulence in a …

Lipid bodies (also known as lipid droplets, adiposomes) are dynamic organelles with key
roles in regulating storage and turnover of lipids in different cells and organisms. The …

Distinct domains in the cell membrane, termed rafts, emerge as central for the infection of
mammalian cells by many pathogens. Rafts consist of sphingolipids and cholesterol that …

Cholesterol‐and sphingolipid‐rich membrane microdomains (lipid rafts) are widely
recognized as portals for pathogenic micro‐organisms. A growing body of evidence …

In the last twenty years, the general view of the plasma membrane has changed from a
homogeneous arrangement of lipids to a mosaic of microdomains. It is currently thought that …