Auto-inflammatory and autoimmune diseases of the musculoskeletal system can be
perceived as a spectrum of rheumatic diseases, with the joints and connective tissues are …

Oxidized phospholipids that result from tissue injury operate as immunomodulatory signals
that, depending on the context, lead to proinflammatory or anti-inflammatory responses. In …

Environmental influences, either social or physical, can affect any aspect of human health,
from disease onset (accumulating in their effects throughout life span) to disease …

A coordinated balance between the positive and negative regulation of pattern-recognition
receptor (PRR)-initiated innate inflammatory responses is required to ensure the most …

IFN-γ has been found to be robustly important to disease pathogenesis in both idiopathic
and induced models of murine lupus. In transgenic mice, over production of IFN-γ in the skin …

This review examines the current literature on the effects of atmospheric particulate matter
(PM) on autoimmune disease and proposes a new role for the aryl hydrocarbon receptor …

Infectious triggers are associated with the induction of transient antiphospholipid antibodies.
One therefore wonders if microbes that permanently colonize us play a role in the …

IFN-γ is essential for idiopathic and murine mercury-induced systemic autoimmunity
(mHgIA), and heterozygous IFN-γ+/− mice also exhibit reduced disease. This suggests that …

To fulfill their roles of surveillance and protecting the host from pathogens, phagocytes are
faced with the challenging task of detecting invaders, distinguishing harmful from innocuous …

Recent studies support the previously established positive associations between
environmental factors and most of the autoimmune diseases. Nevertheless, further studies …