Mechanisms of disease: mechanism-based classification of neuropathic pain—a critical analysis

NB Finnerup, TS Jensen - Nature Clinical Practice Neurology, 2006 - nature.com
Classification of neuropathic pain according to etiology or localization has clear limitations.
The discovery of specific molecular and cellular events following experimental nerve injury …

Mechanisms of disease: neuropathic pain—a clinical perspective

R Baron - Nature clinical practice Neurology, 2006 - nature.com
Neuropathic pain syndromes—pain after a lesion or disease of the peripheral or central
nervous system—are clinically characterized by spontaneous and evoked types of pain …

Neuropathic pain: clinical characteristics and diagnostic workup

P Hansson - European Journal of Pain, 2002 - Elsevier
Neuropathic pain is part of the neurological disease spectrum and may be an expression of
severe medical pathology. Painful neuropathies have multiple disguises and may to a …

Translation of symptoms and signs into mechanisms in neuropathic pain

TS Jensen, R Baron - Pain, 2003 - journals.lww.com
For centuries, clinicians have been taught to examine and classify patients on the basis of
topographical lesion and the underlying pathology. In most clinical specialities, such an …

Painful neuropathies

C Sommer - Current opinion in neurology, 2003 - journals.lww.com
Advances in the standardization of assessment of patients with painful neuropathies are
beginning to have an impact on how clinical studies are designed. Major progress has been …

Pathophysiological mechanisms of neuropathic pain

A Truini, G Cruccu - Neurological Sciences, 2006 - Springer
It is largely acknowledged that multiple and complex pathophysiological mechanisms may
be at play in neuropathic pain. This short review summarises the current understanding of …

Neuropathic pain: spotlighting anatomy, experimental models, mechanisms, and therapeutic aspects

S Kankowski, C Grothe… - European Journal of …, 2021 - Wiley Online Library
Abstract The International Association for the Study of Pain defines neuropathic pain as
“pain arising as a direct consequence of a lesion or disease affecting the somatosensory …

The evolving nature of neuropathic pain: individualizing treatment

HS Smith, CN Sang - European journal of Pain, 2002 - Elsevier
While it may be convenient to categorize neuropathic pain syndromes on the basis of
anatomical distribution or disease state (eg, diabetic neuropathy, radiculopathy, postherpetic …

Dissecting out mechanisms responsible for peripheral neuropathic pain: implications for diagnosis and therapy

CJ Woolf - Life sciences, 2004 - Elsevier
Peripheral neuropathic pain, that clinical pain syndrome associated with lesions to the
peripheral nervous system, is characterized by positive and negative symptoms. Positive …

Therapeutic targets for the management of peripheral nerve injury-induced neuropathic pain

A Singh Jaggi, N Singh - … Formerly Current Drug Targets-CNS & …, 2011 - ingentaconnect.com
Neuropathic pain is a debilitating form of treatment resistant chronic pain and responds
poorly to the clinically available therapies. Studies from animal models of neuropathic pain …