Hydrogenases are enzymes capable of catalyzing the oxidation of molecular hydrogen or its
production from protons and electrons according to the reversible reaction: H2⇌ 2H++ 2e …

Many microorganisms can use molecular hydrogen as a source of electrons or generate it
by reducing protons. These reactions are catalysed by metalloenzymes of two types: NiFe …

The distribution of [Fe]-hydrogenases was once thought to be limited to a small number of
bacteria and a few peculiar hydrogen-producing anaerobic eukaryotes. However, it is now …

Hydrogenases are proteins which catalyze the reversible two-electron oxidation of the most
simple of chemical compounds, molecular hydrogen, following the reaction: H 2⇔ 2H++ …

Hydrogenases catalyse redox reactions with molecular hydrogen, either as substrate or
product. The enzymes harness hydrogen as a reductant using metals that are abundant and …

Hydrogenases are proteins which metabolize the most simple of chemical compounds,
molecular hydrogen, according to the reaction H2↔ 2H++ 2e−. These enzymes are found in …

Hydrogenases catalyze the reversible conversion of molecular hydrogen to protons and
electrons via a heterolytic splitting mechanism. The active sites of [NiFe] hydrogenases …

The activation of molecular hydrogen is of interest both from a chemical and biological
viewpoint. The covalent bond of H2 is strong (436 kJ mol− 1). Its cleavage is catalyzed by …

Biological formation and consumption of molecular hydrogen (H2) are catalyzed by
hydrogenases, of which three phylogenetically unrelated types are known:[NiFe] …

Crystallographic data on the [NiFe] hydrogenase from Desulfovibrio gigas are presented that
provide new information on the structure and mode of action of its dihydrogen activating …