[PDF][PDF] Upregulation of Nrf2/HO-1 signaling and attenuation of oxidative stress, inflammation, and cell death mediate the protective effect of apigenin against …
Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …
Upregulation of Nrf2/HO-1 signaling and attenuation of oxidative stress, inflammation, and cell death mediate the protective effect of apigenin against …
Liver injury is among the adverse effects of the chemotherapeutic agent cyclophosphamide
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …
(CP). This study investigated the protective role of the flavone apigenin (API) against CP …
Apigenin alleviated acetaminophen‐induced hepatotoxicity in low protein‐fed rats: targeting oxidative stress, STAT3, and apoptosis signals
WR Mohamed, AS Kotb… - … of biochemical and …, 2020 - Wiley Online Library
Apigenin (API) is a natural flavonoid abundant in fruits and vegetables. The present study
was undertaken to evaluate the effect of protein malnutrition (PMN) on acetaminophen …
was undertaken to evaluate the effect of protein malnutrition (PMN) on acetaminophen …
Galangin activates Nrf2 signaling and attenuates oxidative damage, inflammation, and apoptosis in a rat model of cyclophosphamide-induced hepatotoxicity
Cyclophosphamide (CP) is a widely used chemotherapeutic agent; however, its clinical
application is limited because of its multi-organ toxicity. Galangin (Gal) is a bioactive …
application is limited because of its multi-organ toxicity. Galangin (Gal) is a bioactive …
Hepatoprotective Effect of Apigenin Against Liver Injury via the Non-canonical NF-κB Pathway In Vivo and In Vitro
S Yue, N Xue, H Li, B Huang, Z Chen, X Wang - Inflammation, 2020 - Springer
Apigenin, a flavonoid found in many plants, has various biological properties. We aimed to
investigate the anti-inflammatory and anti-oxidative activity of apigenin against carbon …
investigate the anti-inflammatory and anti-oxidative activity of apigenin against carbon …
Shikonin attenuates acetaminophen-induced hepatotoxicity by upregulation of Nrf2 through Akt/GSK3β signaling
H Li, Y Chen, J Zhang, X Chen, Z Li, B Liu, L Zhang - Molecules, 2018 - mdpi.com
Acetaminophen (APAP) overdose-induced acute liver damage is mostly due to
overwhelmingly increased oxidative stress. Nuclear factor-erythroid 2-related factor2 (Nrf2) …
overwhelmingly increased oxidative stress. Nuclear factor-erythroid 2-related factor2 (Nrf2) …
Corilagin alleviates acetaminophen-induced hepatotoxicity via enhancing the AMPK/GSK3β-Nrf2 signaling pathway
H Lv, L Hong, Y Tian, C Yin, C Zhu, H Feng - Cell communication and …, 2019 - Springer
Background Acetaminophen (APAP) overdose-induced acute liver failure (ALF) is mainly
resulted from uncontrolled oxidative stress. Nuclear factor-erythroid 2-related factor 2 (Nrf2) …
resulted from uncontrolled oxidative stress. Nuclear factor-erythroid 2-related factor 2 (Nrf2) …
The effect of natural antioxidants in cyclophosphamide-induced hepatotoxicity: Role of Nrf2/HO-1 pathway
IO Sherif - International immunopharmacology, 2018 - Elsevier
Hepatotoxicity induced by cyclophosphamide (Cyclo) is a major concern in clinical practice.
This study was designed to investigate the possible cytoprotective effect of natural …
This study was designed to investigate the possible cytoprotective effect of natural …
Protective effect of arbutin against cyclophosphamide-induced oxidative stress, inflammation, and hepatotoxicity via Nrf2/HO-1 pathway in rats
RS Alruhaimi - Environmental Science and Pollution Research, 2023 - Springer
Cyclophosphamide (CP) is a potent anticancer drug widely employed in chemotherapy
against various types of cancer. However, CP leads to toxicity to non-targeted organs …
against various types of cancer. However, CP leads to toxicity to non-targeted organs …
Isoorientin ameliorates APAP-induced hepatotoxicity via activation Nrf2 antioxidative pathway: The involvement of AMPK/Akt/GSK3β
X Fan, H Lv, L Wang, X Deng, X Ci - Frontiers in pharmacology, 2018 - frontiersin.org
Oxidative stress has been highlighted as therapeutic targets for acetaminophen (APAP)-
induced hepatotoxicity. Isoorientin (Iso), a well-known flavonoid-like compound, has been …
induced hepatotoxicity. Isoorientin (Iso), a well-known flavonoid-like compound, has been …