Despite its effectiveness in treating inflammatory diseases and various malignancies,
methotrexate (MTX) is well known to cause hepatotoxicity, which involves increased …

Abstract Background Cirsii Japonici Herba Carbonisata (Dajitan in Chinese) has been used
to treat liver disorders in Asian countries. Pectolinarigenin (PEC), an abundant constituent in …

Acetaminophen (APAP) overdose is one of the most common causes of drug‐induced acute
liver failure in humans. To investigate the hepatoprotective effect of salvianolic acid C (SAC) …

Acetaminophen (APAP)-induced hepatotoxicity is the main cause of drug-induced liver
injury. This study investigated the protection of baicalin and its aglycone baicalein against …

Hepatic ischemia/reperfusion (I/R) injury is an unavoidable complication of liver
hepatectomy, transplantation, and systemic shock. Pectolinarigenin (Pec) is a flavonoid with …

Acetaminophen (APAP) is a widely used analgesic and antipyretic drug that leads to severe
hepatotoxicity at excessive doses. Fucoidan, a sulfated polysaccharide derived from brown …

Hepatic ischemia/reperfusion (HIR) is the most common type of liver injury following several
clinical situations. Modulating oxidative stress and inflammation by Nrf2/HO-1 and …

Acetaminophen (APAP) overdose is a major cause of drug-induced liver injury worldwide.
Our current study was performed to assess the potential protective effects of γ-oryzanol …

Simple Summary Acetaminophen overdose causes acute liver injury by excessive oxidative
stress. The present study examines the mechanisms underlying the protective effect of …

Background Oxidative stress-triggered fatal hepatotoxicity is an essential pathogenic factor
in acute liver failure (ALF). Aims To investigate the protective effect of daphnetin (Daph) on …