Chondrocyte apoptosis is known to contribute to articular cartilage damage in osteoarthritis
and is correlated to a number of cartilage disorders. Micromass cultures represent a …

Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage
degradation and changes in the subchondral bone. Over the last two decades, there has …

Chondrocyte death and loss of extracellular matrix are the central features in articular
cartilage degeneration during osteoarthritis pathogenesis. Cartilage diseases and, in …

It is conceivable that apoptosis plays a relevant role in the pathogenesis of osteoarthrosis.
We have dissected certain ultrastructural changes in apoptosis when comparing …

Apoptosis, or programmed cell death, plays an important role in many normal and
pathologic conditions. This article has been designed to introduce the concept of …

Osteoarthritis (OA) is the most common joint disease characterised by degradation of
articular cartilage and bone remodelling. For almost a decade chondrocyte apoptosis has …

Recent investigations into the striking heterogeneity of cellular reaction patterns that are
characteristic for, and puzzling in, osteoarthritic cartilage degeneration addressed apoptotic …

This study addresses the occurrence and significance of chondrocyte apoptosis in the
pathogenesis of cartilage destruction. Chondrocyte apoptosis can be inducedin vitroby nitric …

Evidence has accumulated in recent years that programmed cell death (PCD) is not
necessarily synonymous with the classical apoptosis, as defined by Kerr and Wyllie, but that …

Osteoarthritis (OA) is a joint pathology characterized by progressive cartilage degradation.
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …