Sodium citrate 4% locking solution for central venous dialysis catheters—an effective, more cost-efficient alternative to heparin

L Grudzinski, P Quinan, S Kwok… - Nephrology Dialysis …, 2007 - academic.oup.com
Background. Thrombosis of the central venous haemodialysis catheter compromises
dialysis adequacy and catheter survival. Heparin containing catheter-locking solution has …

Trisodium citrate 4%—an alternative to heparin capping of haemodialysis catheters

CE Lok, D Appleton, C Bhola, B Khoo… - Nephrology Dialysis …, 2007 - academic.oup.com
Abstract Background. Central venous catheters (CVCs) continue to be used at a high rate for
dialysis access and are frequently complicated by thrombus-related malfunction …

Randomized, clinical trial comparison of trisodium citrate 30% and heparin as catheter-locking solution in hemodialysis patients

MC Weijmer, MA Van Den Dorpel… - Journal of the …, 2005 - journals.lww.com
Interdialytic hemodialysis catheter-locking solutions could contribute to a reduction of
catheter-related complications, especially infections. However, they can cause side effects …

Concentrated sodium citrate (23%) for catheter lock

SR Ash, RA Mankus, JM Sutton… - Hemodialysis …, 2000 - Wiley Online Library
For chronic central venous dialysis catheters, the standard method for maintaining catheter
patency between treatments is to instill (lock) catheters with 5000–10 000 units of heparin in …

A comparative prospective study on the use of low concentrate citrate lock versus heparin lock in permanent dialysis catheters

L Hendrickx, D Kuypers, P Evenepoel… - … journal of artificial …, 2001 - journals.sagepub.com
We prospectively evaluated the efficacy and safety of a low concentrate citrate lock versus
heparin lock in permanent single lumen hemodialysis catheters. The frequency of clot …

Sodium citrate 4% versus heparin as a lock solution in hemodialysis patients with central venous catheters

CK Yon, CL Low - American journal of health-system pharmacy, 2013 - academic.oup.com
Purpose The effects of heparin versus sodium citrate 4% as a lock solution on catheter-
related infections (CRIs), catheter patency, and hospitalizations in long-term hemodialysis …

The effect of heparinized catheter lock solutions on systemic anticoagulation in hemodialysis patients.

PC Thomson, ST Morris, RA Mactier - Clinical nephrology, 2011 - europepmc.org
Background Hemodialysis catheter thrombosis is associated with loss of catheter patency,
catheter-related bacteremia and sepsis. To limit these risks, many renal units use heparin as …

A prospective, randomized, double-blind crossover study on the use of 5% citrate lock versus 10% citrate lock in permanent hemodialysis catheters

G Meeus, DRJ Kuypers, K Claes, P Evenepoel… - Blood purification, 2005 - karger.com
Central venous catheters are used as permanent vascular access for chronic hemodialysis
when construction of an arteriovenous fistula is not possible or contraindicated. We …

Concentration of heparin-locking solution and risk of central venous hemodialysis catheter malfunction

CM Thomas, J Zhang, TH Lim, N Scott-Douglas… - ASAIO …, 2007 - journals.lww.com
Heparin is used as an interdialytic locking solution for hemodialysis (HD) central venous
catheters (CVCs). The purpose of this study was to compare effectiveness of two heparin …

Locking solutions for hemodialysis catheters; heparin and citrate—a position paper by ASDIN

JE Moran, SR Ash… - Seminars in …, 2008 - Wiley Online Library
There is wide variation in the use of solutions to “lock” or fill tunneled central venous
catheters for dialysis. Some centers use undiluted heparin concentrations ranging from 1000 …