Importance Sickle cell disease (SCD) is a life-threatening genetic disorder affecting nearly
100 000 individuals in the United States and is associated with many acute and chronic …

Family physicians are the primary and sometimes only health care resource for families
affected by sickle cell disease. Recently published guidelines provide important …

The application of evidence-based medicine to the management of adults with sickle cell
disease (SCD) is currently primarily driven by clinical expertise and patient preference, as …

Sickle cell disease (SCD) is the most common inherited blood disorder and affects
approximately 100,000 individuals in the United States, primarily those of racial and ethnic …

Sickle cell disease afflicts millions of people worldwide and approximately 100,000
Americans. Complications are myriad and arise as a result of complex pathological …

Background: Sickle cell disease (SCD) is a life-limiting inherited hemoglobinopathy that
results in significant complications and affects quality of life. Hematopoietic stem cell …

Importance Sickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized
by formation of long chains of hemoglobin when deoxygenated within capillary beds …

[French guidelines for the management of adult sickle cell disease: 2015 update]. - Abstract
- Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About Tools …

Hydroxyurea has proven efficacy in numerous clinical trials as a disease-modifying
treatment for patients with sickle cell anemia (SCA) but is currently under-used in clinical …

In the United States, sickle cell disease affects approximately 1 in 350 African-American
newborn infants each year, and approximately 72,000 individuals total. Sickle cell disease is …