T cell migration in rheumatoid arthritis

M Mellado, L Martínez-Muñoz, G Cascio… - Frontiers in …, 2015 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation
in joints, associated with synovial hyperplasia and with bone and cartilage destruction …

Inflammatory cell migration in rheumatoid arthritis: a comprehensive review

E Nevius, AC Gomes, JP Pereira - Clinical reviews in allergy & …, 2016 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily
affects the joints. Self-reactive B and T lymphocytes cooperate to promote antibody …

Effector functions of CD4+ T cells at the site of local autoimmune inflammation—lessons from rheumatoid arthritis

K Chemin, C Gerstner, V Malmström - Frontiers in immunology, 2019 - frontiersin.org
Infiltration of memory CD4+ T cells in synovial joints of Rheumatoid Arthritis (RA) patients
has been reported since decades. Moreover, several genome wide association studies …

Cell-cell interactions in synovitis Interactions between T lymphocytes and synovial cells

IB McInnes, BP Leung, FY Liew - Arthritis Research & Therapy, 2000 - Springer
Mechanisms whereby T lymphocytes contribute to synovial inflammation in rheumatoid
arthritis are poorly understood. Here we review data that indicate an important role for cell …

The Interplay Between Monocytes/Macrophages and CD4+ T Cell Subsets in Rheumatoid Arthritis

CA Roberts, AK Dickinson, LS Taams - Frontiers in immunology, 2015 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by inflammation
of the synovial lining (synovitis). The inflammation in the RA joint is associated with and …

Understanding the dynamics: pathways involved in the pathogenesis of rheumatoid arthritis

E Choy - Rheumatology, 2012 - academic.oup.com
RA is a progressive inflammatory autoimmune disease with articular and systemic effects. Its
exact cause is unknown, but genetic and environmental factors are contributory. T cells, B …

Migration and homeostasis of regulatory T cells in rheumatoid arthritis

K Kotschenreuther, S Yan, DM Kofler - Frontiers in Immunology, 2022 - frontiersin.org
Regulatory T (Treg) cells are garnering increased attention in research related to
autoimmune diseases, including rheumatoid arthritis (RA). They play an essential role in the …

Where do T cells stand in rheumatoid arthritis?

C Fournier - Joint Bone Spine, 2005 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by destruction of
cartilage and bone. The destructive lesions result from both immune responses and non …

Enrichment of differentiated CD45RBdim, CD27 – memory T cells in the peripheral blood, synovial fluid, and synovial tissue of patients with rheumatoid arthritis

CL Kohem, RI Brezinschek, H Wisbey… - Arthritis & …, 1996 - Wiley Online Library
Objective. To delineate in greater detail the phenotype of T cells that reside in the synovial
tissue (ST) and synovial fluid (SF) of patients with rheumatoid arthritis (RA), in order to …

T cells in osteoarthritis: alterations and beyond

Y Li, W Luo, S Zhu, G Lei - Frontiers in immunology, 2017 - frontiersin.org
Although osteoarthritis (OA) has been traditionally regarded as a non-inflammatory disease,
reports increasingly suggest that it is inflammatory, at least in certain patients. OA patients …