NLRP3 inflammasome pathway involved in the pathogenesis of metabolic associated fatty liver disease
The prevalence of Metabolic-associated fatty liver disease (MAFLD) has been steadily
increasing worldwide, paralleling the global epidemic of obesity and diabetes. It is estimated …
increasing worldwide, paralleling the global epidemic of obesity and diabetes. It is estimated …
NLRP3 inflammasome activation is required for fibrosis development in NAFLD
A Wree, MD McGeough, CA Peña, M Schlattjan… - Journal of molecular …, 2014 - Springer
NLR inflammasomes, caspase 1 activation platforms critical for processing key pro-
inflammatory cytokines, have been implicated in the development of nonalcoholic fatty liver …
inflammatory cytokines, have been implicated in the development of nonalcoholic fatty liver …
NACHT-LRR-PYD-containing proteins 3 inflammasome and nonalcoholic fatty liver disease
XJ Gao, S Lin, YY Zhu - Zhonghua gan Zang Bing za zhi= Zhonghua …, 2016 - europepmc.org
NACHT-LRR-PYD-containing proteins 3 (NLRP3) inflammasome regulates the maturation
and secretion of proinflammatory cytokines including interleukin-1β and interleukin-18, as …
and secretion of proinflammatory cytokines including interleukin-1β and interleukin-18, as …
NLRC4 inflammasome activation regulated by TNF-α promotes inflammatory responses in nonalcoholic fatty liver disease
Y Chen, K Ma - Biochemical and biophysical research communications, 2019 - Elsevier
The prevalence of nonalcoholic fatty liver disease (NAFLD) is high and increasing
throughout the world. The intense sterile inflammation stemming from steatosis plays a …
throughout the world. The intense sterile inflammation stemming from steatosis plays a …
Enhanced inflammasome-mediated inflammation and impaired autophagy in peripheral blood mononuclear cells is associated with non-alcoholic fatty liver disease …
Aims Identification of the progress of non-alcoholic fatty liver disease (NAFLD) is crucial for
their effective treatment. Circulating peripheral blood mononuclear cells (PBMC) could be a …
their effective treatment. Circulating peripheral blood mononuclear cells (PBMC) could be a …
Role of NLRP3 Inflammasome in the Progression of NAFLD to NASH
X Wan, C Xu, C Yu, Y Li - Canadian Journal of …, 2016 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) has been recognized as a major public health
problem worldwide. Nonalcoholic steatohepatitis (NASH) is an advanced form of NAFLD …
problem worldwide. Nonalcoholic steatohepatitis (NASH) is an advanced form of NAFLD …
[HTML][HTML] Inhibition of hepatic NLRP3 inflammasome ameliorates non-alcoholic steatohepatitis/hepatitis B-induced hepatic injury
F Chen, Y Liu, Q Li, F Wang - Clinics and Research in Hepatology and …, 2023 - Elsevier
Background and aim Both chronic hepatitis B (CHB) and non-alcoholic fatty liver disease
(NAFLD)/non-alcoholic steatohepatitis (NASH) are the most common liver diseases over the …
(NAFLD)/non-alcoholic steatohepatitis (NASH) are the most common liver diseases over the …
Hepatic nucleotide binding oligomerization domain‐like receptors pyrin domain‐containing 3 inflammasomes are associated with the histologic severity of non …
H Mitsuyoshi, K Yasui, T Hara, H Taketani… - Hepatology …, 2017 - Wiley Online Library
Aim To examine the role of nucleotide binding oligomerization domain‐like receptor family
pyrin domain‐containing 3 (NLRP3) inflammasomes in the development of non‐alcoholic …
pyrin domain‐containing 3 (NLRP3) inflammasomes in the development of non‐alcoholic …
A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet
The activation of NOD-like receptor family pyrin domain containing 3 (NLRP3)
inflammasome is closely associated with the development and progression of non-alcoholic …
inflammasome is closely associated with the development and progression of non-alcoholic …
The NLRP3 inflammasome in non-alcoholic fatty liver disease and steatohepatitis: Therapeutic targets and treatment
L Yu, W Hong, S Lu, Y Li, Y Guan, X Weng… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is among the most prevalent primary liver
diseases worldwide and can develop into various conditions, ranging from simple steatosis …
diseases worldwide and can develop into various conditions, ranging from simple steatosis …