The co‐ordinated regulation of heat shock proteins is critically important for the stress
response of M. tuberculosis, failure of which results in enhanced immune recognition of the …

ABSTRACT A hallmark feature of Mycobacterium tuberculosis pathogenesis lies in the
ability of the pathogen to survive within macrophages under a stressful environment. Thus …

Regulation of the expression of heat-shock proteins plays an important role in the
pathogenesis of Mycobacterium tuberculosis. The heat-shock response of bacteria involves …

Regulating responses to stress is critical for all bacteria, whether they are environmental,
commensal, or pathogenic species. For pathogenic bacteria, successful colonization and …

Coordinated regulation of molecular chaperones is an important feature of the bacterial
stress response. The small molecular chaperone gene acr2 of Mycobacterium tuberculosis …

Tuberculosis is a worldwide health problem, given that one-third of the world's population is
currently infected with Mycobacterium tuberculosis. Understanding the regulation of …

Unlike many pathogens that are overtly toxic to their hosts, the primary virulence determinant
of Mycobacterium tuberculosis appears to be its ability to persist for years or decades within …

Heat shock proteins (Hsps) are a highly conserved family of proteins. The regulation of
expression of Hsps in Mycobacterium tuberculosis, is regulated both positively and …

The regulation of heat shock protein (HSP) expression is critically important to pathogens
such as Mycobacterium tuberculosis and dysregulation of the heat shock response results in …

HspR is a repressor known to control expression of heat shock operons in a number of
Eubacteria. In mycobacteria and in several other actinobacteria, this protein is synthesized …