Introduction Osteoarthritis (OA) is a common disease worldwide leading to significant
morbidity. The underlying disease process is multifactorial however there is increasing focus …

Background Osteoarthritis (OA) is the most orthopedic condition. The pattern of gene
expression and the transcription factors that exert control of chondrogenesis have been …

Objective To evaluate the underlying function of microRNAs (miRNAs) in osteoarthritis (OA).
Design A bioinformatic analysis of miRNAs-OA studies was completed in multiple …

Micro ribonucleic acid (microRNA) regulation and expression has become an emerging field
in determining the mechanisms regulating a variety of inflammation-mediated diseases …

Osteoarthritis (OA) is the most prevalent degenerative joint disease and is accompanied by
pain and joint dysfunction. Its clinical treatment tends to be unsatisfactory. Novel targets in …

MicroRNA (miRNA) is a class of noncoding RNA that exhibits tissue-or developmental stage-
specific expression patterns and negatively regulates gene expression. MiRNAs play an …

An imbalance in gene expressional events skewing chondrocyte anabolic and catabolic
pathways toward the latter causes an aberrant turnover and loss of extracellular matrix …

MicroRNAs are small double-stranded RNAs, which negatively regulate gene expression
and have been shown to have key roles in both chondrocyte development and cartilage …

Osteoarthritis (OA) is a chronic disease and its etiology is complex. With increasing OA
incidence, more and more people are facing heavy financial and social burdens from the …

MicroRNAs (miRNAs), a class of endogenous single-stranded short noncoding RNAs, have
emerged as vital epigenetic regulators of both pathological and physiological processes in …